Gene interactions and pathways from curated databases and text-mining

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CTSK — TNFRSF11B

Text-mined interactions from Literome

Wittrant et al., Biochem Biophys Res Commun 2002 : This study investigated the direct effects of human OPG on cathepsin K , MMP-9, MMP-2, and tissue inhibitors of metalloproteinases ( TIMP1 and TIMP2 ) expressed by purified rabbit osteoclasts
Kerschan-Schindl et al., Exp Gerontol 2005 (Bone Resorption) : Thus, the age related increase in OPG , which markedly inhibits the expression of cathepsin K, may also reduce serum levels of cathepsin K
Zhang et al., Bone 2009 (Weight Gain) : Ovariectomy promoted the mRNA expression of alpha-1 type I collagen (COL), osteoprotegerin (OPG) and receptor activator of nuclear factor-kappa B ligand ( RANKL ) ; and inhibited the mRNA expression of cathepsin K and matrix metalloproteinase-9 (MMP-9) in the proximal tibia of aged rats