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CTSK — TNFRSF11B
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Wittrant et al., Biochem Biophys Res Commun 2002
:
This study investigated the direct
effects of human
OPG on
cathepsin K , MMP-9, MMP-2, and tissue inhibitors of metalloproteinases ( TIMP1 and TIMP2 ) expressed by purified rabbit osteoclasts
Kerschan-Schindl et al., Exp Gerontol 2005
(Bone Resorption) :
Thus, the age related increase in
OPG , which markedly inhibits the expression of cathepsin K, may also
reduce serum levels of
cathepsin K
Zhang et al., Bone 2009
(Weight Gain) :
Ovariectomy promoted the mRNA expression of alpha-1 type I collagen (COL),
osteoprotegerin (OPG) and receptor activator of nuclear factor-kappa B ligand ( RANKL ) ; and
inhibited the mRNA expression of
cathepsin K and matrix metalloproteinase-9 (MMP-9) in the proximal tibia of aged rats