Xu et al., J Biol Chem 2007
:
p27 , an important cell cycle regulator, blocks the G ( 1 ) /S transition in cells by binding and inhibiting Cdk2/cyclin A and Cdk2/cyclin E complexes (Cdk2/E)
Song et al., Diabetes 2008
:
Cyclin A2 overexpression in primary islets increased proliferation and reduced p27