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ECM1 — FGF2

Text-mined interactions from Literome

Kim et al., FEBS Lett 2005 : In the presence of FGF2 , which is normally required for proliferation in an undifferentiated state, inhibition of phosphatidylinositol 3-kinase (PI3K)/Akt/PKB signal stimulated differentiation and attenuated the expression of extracellular matrix ( ECM ) molecules
Nur-E-Kamal et al., Mol Cell Biochem 2008 : Activation of fibroblast growth factor receptors ( FGFRs ) requires the formation of a ternary complex between fibroblast growth factors ( FGFs ), FGFRs, and heparan sulfate proteoglycans, which are all located on the cell surface and the basement membrane ( BM ) /extracellular matrix ( ECM )
Shimizu et al., J Gastroenterol Hepatol 2008 (Fibrosis...) : Platelet derived growth factor ( PDGF ) is a potent stimulator of PSC proliferation, and transforming growth factor-beta, PDGF, and basic fibroblast growth factor stimulate ECM synthesis by PSC
Sommer et al., Graefes Arch Clin Exp Ophthalmol 2008 : The observed opposite effects of bFGF and TGF-beta1 on hyalocyte proliferation and ECM accumulation may allow for the control of hyaloycte properties
Uchii et al., Arthritis Res Ther 2008 (Disease Models, Animal...) : In cultured chondrocytes, FGF8 induced the release of matrix metalloproteinase 3 and prostaglandin E2, and caused degradation of the ECM
Etheredge et al., Invest Ophthalmol Vis Sci 2009 : The effects of IGF-I, TGF-beta1, FGF-2 , and PDGF on proliferation and ECM production by primary cultured bovine keratocytes were evaluated
Shi et al., PloS one 2013 (Cicatrix, Hypertrophic) : bFGF regulated extracellular matrix ( ECM ) synthesis and degradation via interference in the collagen distribution, the a-smooth muscle actin ( a-SMA ) and transforming growth factor-1 ( TGF-ß1 ) expression
Hitraya et al., Lab Invest 1995 : Next we studied the separate effect of heparin and aFGF or bFGF on the expression of ECM genes in HDMVEC ... Heparin alone decreased the mRNA levels for these genes by 60, 77, and 65 %, respectively ; however, FGF potentiated the negative effect of heparin on ECM gene expression ... The data also demonstrate that heparin, ECGF supplement, aFGF, and bFGF regulate ECM gene expression in HDMVEC in vitro and suggest that these growth factors may modulate the expression of matrix genes in vivo
Oh et al., Brain Res 1997 : In the current study, we have addressed the involvement of PKC in the bFGF- and astrocyte ECM- enhanced process formation by adult human OLs by using a selective inhibitor of PKC, calphostin C
Hosokawa et al., Endocrinology 1998 : The phorbol ester TPA, and basic fibroblast growth factor, dramatically suppress cAMP induced production of progesterone, whereas bovine corneal endothelial cell ECM ( BCE/ECM ) enhanced cAMP induced progesterone and antagonized basic fibroblast growth factor suppression of cAMP induced steroidogenesis