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LGALS1 — MMP2
Text-mined interactions from Literome
Wu et al., Mol Cancer Res 2009
(Adenocarcinoma...) :
We conclude that
Gal-1 is
involved in tumor invasion and metastasis by increasing
MMP expression and reorganizing cytoskeletons in oral cancers and lung adenocarcinoma
Kim et al., Eur J Cancer 2012
(Neoplasm Invasiveness...) :
When we evaluated the interaction between fibroblasts ( T HESCs ) and cancer cells ( A2780-CP20 ), we found that
MMP-2 expression in cancer cells was
affected by
Gal-1 secreted by fibroblast cells, which suggests that Gal-1 in human fibroblasts might affect the invasive abilities of tumour cells