Gene interactions and pathways from curated databases and text-mining

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LGALS1 — MMP2

Text-mined interactions from Literome

Wu et al., Mol Cancer Res 2009 (Adenocarcinoma...) : We conclude that Gal-1 is involved in tumor invasion and metastasis by increasing MMP expression and reorganizing cytoskeletons in oral cancers and lung adenocarcinoma
Kim et al., Eur J Cancer 2012 (Neoplasm Invasiveness...) : When we evaluated the interaction between fibroblasts ( T HESCs ) and cancer cells ( A2780-CP20 ), we found that MMP-2 expression in cancer cells was affected by Gal-1 secreted by fibroblast cells, which suggests that Gal-1 in human fibroblasts might affect the invasive abilities of tumour cells