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MMP2 — VCAM1

Text-mined interactions from Literome

Kambara et al., J Neuroimmunol 1999 (Glioblastoma...) : Although no significant differences were noted in the percentage of VLA-4 positive cells in cultured T cells between HAM patients and control patients with OND, our results indicate that VCAM-1 mediated MMP-2 induction is up-regulated in T cells of HAM patients
Lee et al., J Allergy Clin Immunol 2003 (Asthma...) : An aim of this study was to evaluate the effect of MMP inhibitors on the expression of ICAM-1 and VCAM-1 in the migration of inflammatory cells in a murine model of TDI induced asthma ... We used a murine model to investigate TDI induced asthma to examine the possible involvement of ICAM-1 and VCAM-1 in the pathogenesis of that disease and the effect of MMP inhibitors on the expression of ICAM-1 and VCAM-1 ... These results suggest that MMP inhibitors regulate inflammatory cell migration by reducing ICAM-1 and VCAM-1 expression and possibly also by suppressing IL-1beta, IL-4, and TNF-alpha expression
Madri et al., Biochem Cell Biol 1996 (Inflammation) : We have demonstrated that matrix metalloxproteinase-2 (MMP-2) is induced in T cells upon adhesion to endothelial cells and that the induction of MMP-2 is mediated by binding of T cell VLA-4 to VCAM-1 ... These results demonstrate that binding to VCAM-1 on endothelial cells induces MMP-2 in T cells, which, in turn, may facilitate T cell migration into perivascular tissue