Gene interactions and pathways from curated databases and text-mining

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TANK — TRAF2

Pathways - manually collected, often from reviews:

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

Text-mined interactions from Literome

Chaudhuri et al., Biochem Biophys Res Commun 1999 : We conclude from these studies that the phosphorylation of TRAF2 is likely to play an important role in regulating signaling by virtue of its ability to influence the CD40-TRAF2 interaction
Leonardi et al., J Biol Chem 2000 : TRAF2 is required for TNF induced activation of c-Jun N-terminal kinase/stress activated protein kinase ( JNK/SAPK ), and TRAF2 can also mediate activation of NF-kappaB
Zhu et al., Cytokine 2010 (Glomerulonephritis...) : Knockdown TRAF-2 by siRNA significantly suppressed soluble AIgG induced up-regulation of TRAF-2 , IL-1beta, and IL-6