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IL23A — RELA
Pathways - manually collected, often from reviews:
-
KEGG Tuberculosis:
NFKB1/RELA
→
IL23A
(gene expression, expression)
Text-mined interactions from Literome
Heidemann et al., Am J Physiol Gastrointest Liver Physiol 2007
:
The strongest induction was induced by proinflammatory factors known to utilize the NF-kappaB pathway, and expression of EBI3 and
IL-23p19 was
diminished by an
NF-kappaB inhibitor
Ju et al., J Immunol 2008
(Arthritis, Experimental...) :
IL-23 induces receptor activator of
NF-kappaB ligand expression on CD4+ T cells and promotes osteoclastogenesis in an autoimmune arthritis model
Li et al., Immunol Lett 2010
(Arthritis, Rheumatoid...) :
IL-23 induces receptor activator of
NF-kappaB ligand expression in fibroblast-like synoviocytes via STAT3 and NF-kappaB signal pathways
Fukuda et al., Int J Oncol 2010
(Carcinoma, Squamous Cell...) :
Furthermore, luciferase reporter assay showed that
IL-23 strongly
induces RelA activity, and confirmed this finding by knockdown of IL-23 using RNA interference