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ALB — CCL2
Text-mined interactions from Literome
Wang et al., J Am Soc Nephrol 1999
:
Induction of
monocyte chemoattractant protein-1 by
albumin is mediated by nuclear factor kappaB in proximal tubule cells ... The purpose of this study was to investigate whether nuclear factor kappaB (NFkappaB)/Rel proteins play a role in
albumin induced
MCP-1 transcription
Ichiki et al., Biochem Biophys Res Commun 2000
:
We examined the
effect of glycated serum
albumin ( GA ) on the expression of
monocyte chemoattractant protein-1 ( MCP-1 ) that is an important chemokine recruiting monocyte to blood vessel
Banba et al., Kidney Int 2000
(Albuminuria...) :
Next, using cultured human mesangial cells, we investigated the
role of
Gly-Alb and/or HG on the gene and protein expression of
MCP-1 ... In cultured human mesangial cells, the gene and protein expression of
MCP-1 was dose and time dependently
up-regulated by
Gly-Alb
Bian et al., Invest Ophthalmol Vis Sci 2001
:
Signaling pathways for glycated human serum
albumin induced IL-8 and
MCP-1 secretion in human RPE cells
Takaya et al., American journal of physiology. Renal physiology 2003
(Cell Transformation, Viral) :
Involvement of ERK pathway in
albumin induced
MCP-1 expression in mouse proximal tubular cells ... In this study, we examined whether
albumin overload induced
MCP-1 expression was
regulated by mitogen activated protein kinase ( MAPK ) in mouse proximal tubular ( mProx ) cells
He et al., Zhonghua Yi Xue Za Zhi 2004
(Albuminuria...) :
[ The role of Cubilin in
albumin induced
MCP-1 , RANTES expression by renal tubular epithelial cells ] ... To study the molecular mechanism of
albumin induced
MCP-1 and RANTES expression by renal tubular epithelial cells ( RTECs )
Calvo et al., J Neurosci Res 2005
:
In the present study, we show that ovalbumin and
albumin induce the release of
monocyte chemotactic protein 1 ( MCP-1/CCL2 ) from rat embryonic mixed brain cells ... The
albumin induced
MCP-1 production is significantly inhibited in calphostin C-treated cells, suggesting the implication of a protein kinase C-dependent signaling pathway
Murali et al., American journal of physiology. Renal physiology 2007
(Kidney Failure, Chronic) :
The present study determined whether cellular overexpression of heme oxygenase-1 (HO-1) can influence
albumin stimulated
MCP-1 production ... We conclude that HO-1 overexpression in the proximal tubule reduces
MCP-1 production in
response to
albumin , and this occurs, at least in part, by inhibiting an ERK dependent, NF-kappaB dependent pathway at a site that is distal to the activation of ERK ... These findings suggest that the induction of HO-1 in the proximal tubule, as occurs in chronic kidney disease, may be a countervailing response that reduces
albumin stimulated production of cytokines such as
MCP-1
Mizuno et al., J Cardiovasc Pharmacol 2006
(Body Weight...) :
In a separate study,
albumin increased
MCP-1 release from cultured tubular epithelial cells
Marsche et al., FASEB J 2007
(Inflammation...) :
Hypochlorite modified
albumin colocalizes with RAGE in the artery wall and
promotes MCP-1 expression via the RAGE-Erk1/2 MAP-kinase pathway
Shui et al., Mol Biol Rep 2010
(MAP Kinase Signaling System) :
Mycophenolic acid inhibits
albumin induced
MCP-1 expression in renal tubular epithelial cells through the p38 MAPK pathway
de Borst et al., J Pharmacol Exp Ther 2009
(Disease Models, Animal...) :
In NRK-52E cells, the JNK inhibitor anthra ( 1,9-cd ) pyrazol-6 ( 2H ) -one-1,9-pyrazoloanthrone ( SP600125 ) reduced interleukin-1beta-, transforming growth factor-beta-, or bovine serum
albumin induced
MCP-1 expression in a potent manner ( up to 150-fold )
Lee et al., American journal of physiology. Renal physiology 2011
:
Imatinib also inhibited the
albumin induced mRNA expression of
MCP-1 , VCAM-1, transforming growth factor ( TGF ) -ß1, and collagen I ( a1 )
Strecker et al., Stroke 2013
(Disease Models, Animal...) :
MCP-1-deficiency resulted in reduced infarct sizes and an increased vascular accumulation of
fluorescein-isothiocyanate-albumin
Bian et al., Curr Eye Res 1998
:
Glycated human serum
albumin induces IL-8 and
MCP-1 gene expression in human corneal keratocytes