Gene interactions and pathways from curated databases and text-mining

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CDKN1A — IL1B

Pathways - manually collected, often from reviews:

Text-mined interactions from Literome

Nathe et al., Arterioscler Thromb Vasc Biol 2002 (Arteriosclerosis) : Interleukin-1beta inhibits expression of p21 ( WAF1/CIP1 ) and p27 ( KIP1 ) and enhances proliferation in response to platelet derived growth factor-BB in smooth muscle cells
Shen et al., J Immunol 2004 (Breast Neoplasms) : IL-1beta induces p21 ( Cip1/Waf1 ), which may contribute to its inhibition of IGF-I activated Cdk2
Hwang et al., IUBMB Life 2007 : Overexpression of p21 blocked IL-1beta- or CDK6 induced suppression of type II collagen expression