Xu et al., Biochem Biophys Res Commun 2004
:
TWEAK induced phosphorylation of IkappaBalpha and BAY11-7082, a selective inhibitor of IkappaBalpha phosphorylation, inhibited the TWEAK induced IL-8 and GM-CSF production by BEAS2B cells
Kawakita et al., Biochem Biophys Res Commun 2004
(Carcinoma, Hepatocellular...) :
We found that TWEAK also promotes cell proliferation and induces the secretion of IL-8 and MCP-1 in human umbilical vein endothelial cell
De Ketelaere et al., FEBS Lett 2004
:
We demonstrate that the induction of IL-8 expression by TWEAK can be counteracted by LiCl
Hosokawa et al., Clin Exp Immunol 2006
(Periodontitis) :
The IL-8 and VEGF production induced by TWEAK was augmented synergistically by simultaneous stimulation with transforming growth factor (TGF)-beta1 or IL-1beta
Abend et al., J Virol 2010
:
Finally, the downregulation of TWEAKR by miR-K10a in primary human endothelial cells resulted in a decrease in levels of expression of the proinflammatory cytokines interleukin-8 (IL-8) and monocyte chemoattractant protein 1 ( MCP-1 ) in response to TWEAK