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ADAR — CREB1

Text-mined interactions from Literome

Kittler et al., Neuron 2006 (Ischemic Attack, Transient) : In this issue of Neuron, Peng et al. propose that CREB dependent downregulation of the RNA editing enzyme ADAR2 , resulting in defective Q/R editing of AMPA receptor GluR2 subunits and increased availability of calcium and zinc-permeable death promoting AMPA receptors, underlies the vulnerability of some neuronal populations to ischemia
Peng et al., Neuron 2006 (Disease Models, Animal...) : Recovery of GluR2 Q/R site editing by expression of exogenous ADAR2b gene or a constitutively active CREB , VP16-CREB, which induces expression of endogenous ADAR2 , protects vulnerable neurons in the rat hippocampus from forebrain ischemic insult