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HBB — KLF6
Text-mined interactions from Literome
Basu et al., Blood 2005
:
In mice carrying the entire human globin locus,
KLF2 also
regulates the expression of the human embryonic epsilon-globin gene but not the adult
beta-globin gene, suggesting that this developmental-stage-specific role is evolutionarily conserved
Hodge et al., Blood 2006
(Anemia) :
Erythroid
Kruppel-like factor ( EKLF, KLF1 )
plays an important role in definitive erythropoiesis and
beta-globin gene regulation but failure to rectify lethal fetal anemia upon correction of globin chain imbalance suggested additional critical EKLF target genes