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AOM — MYC
Text-mined interactions from Literome
Kishimoto et al., J Exp Clin Cancer Res 2002
(Colonic Neoplasms...) :
In conclusion,
AOM caused an increase in COX-2 and
c-Myc mRNA expression, a decrease in APC mRNA expression, induction of apoptosis in normal appearing colonic mucosa, and a K-ras mutation in ACF with 4 or more crypts
Fichera et al., J Surg Res 2007
(Adenocarcinoma...) :
Compared with control,
AOM/DSS significantly
increased c-Myc ( 15-fold ), cyclooxygenase 2 (COX-2) ( 2.5-fold ), and pERK ( 10-fold ), and Ro26-2198 abolished these increases