Gene interactions and pathways from curated databases and text-mining

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AOM — MYC

Text-mined interactions from Literome

Kishimoto et al., J Exp Clin Cancer Res 2002 (Colonic Neoplasms...) : In conclusion, AOM caused an increase in COX-2 and c-Myc mRNA expression, a decrease in APC mRNA expression, induction of apoptosis in normal appearing colonic mucosa, and a K-ras mutation in ACF with 4 or more crypts
Fichera et al., J Surg Res 2007 (Adenocarcinoma...) : Compared with control, AOM/DSS significantly increased c-Myc ( 15-fold ), cyclooxygenase 2 (COX-2) ( 2.5-fold ), and pERK ( 10-fold ), and Ro26-2198 abolished these increases