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CDH4 — RHO

Text-mined interactions from Literome

Braga et al., Exp Cell Res 2000 : In order to show efficient adhesion, cadherin receptors require an association with actin filaments and the activity of RHO proteins
Johnson et al., J Biol Chem 2004 : In addition, we show that R-cadherin induces cell motility when expressed in epithelial cells and that this increased motility is dependent upon Rho GTPase activity
Smith et al., Mol Biol Cell 2012 : These data are consistent with a model in which p120 dynamically regulates Rho-GTPase activity at the cadherin complex through transient interaction with several of its up- and downstream effectors, including ROCK1
Bonacci et al., Cell Signal 2012 : Small GTPase Rho regulates R-cadherin through Dia1/profilin-1 ... This study examines regulation of R-cadherin adherens junctions by the small GTPase Rho and its downstream effectors in MDA-MB-231 breast cancer cells, MDA-MB-231 cells stably expressing the N-terminus of c-Cbl, and MCF10A normal breast epithelial cells ... We find that the small GTPase Rho regulates R-cadherin adherens junction formation via Dia1 ( also known as p140mDia ) and profilin-1 mediated signaling pathway