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MMP2 — RHO

Text-mined interactions from Literome

Koike et al., Biochem Biophys Res Commun 2000 : However, neither C3 transferase, a Rho inhibitor, nor Y-27632, a specific inhibitor of Rho-kinase, induced MMP-2 activation
Deroanne et al., J Cell Sci 2005 : By contrast, MMP-2 and type-I-collagen expression was not affected by the individual silencing of each Rho GTPase
Do et al., Mol Cancer Res 2007 (Ovarian Neoplasms) : Inhibition of Rho-kinase/ROCK enhanced both LPA stimulated loss of stress fibers and pro-MMP-2 activation
Xue et al., Hepatology research : the official journal of the Japan Society of Hepatology 2008 : Our aim was to test the anticancer effects of Rho/ROCK inhibitor, Y-27632, including possible mechanisms in a highly metastasizing hepatocellular carcinoma ( HCC ) mouse model on its secretion of matrix metalloproteinase ( MMP ) and tumor progression
Adiguzel et al., Matrix Biol 2013 : Inhibition of Rho restored MMP-2 activity in the Col8 ( -/- ) cells, and partially rescued migration, demonstrating that the elevations in RhoA activity were responsible for the suppression of migration of these cells