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MMP2 — MT1JP

Text-mined interactions from Literome

Ellerbroek et al., Cancer Res 1999 (Ovarian Neoplasms) : Aggregation of beta1 integrins with immobilized 21C8 or P4C10 antibodies stimulated MMP dependent pro-MMP-2 activation and accumulation of a M ( r ) 43,000 form of membrane type 1 MMP (MT1-MMP) , a cell surface activator of pro-MMP-2, in cell extracts
Matsumoto et al., Jpn J Cancer Res 2001 (Bone Neoplasms...) : MMP2 is activated by membranous type-1 MMP (MT1-MMP) and type-2 tissue inhibitor of MMP ( TIMP2 )
McLennan et al., Diabetes 2002 (Diabetic Nephropathies) : Also examined were membrane type 1 MMP (MT1-MMP) , tissue inhibitors of MMPs (TIMP)-1 and -2, and transforming growth factor-beta ( TGF-beta ), which together regulate MMP-2 activities in an interacting manner
Zucker et al., Exp Cell Res 2004 (Fibrosarcoma) : Binding of tissue inhibitor of metalloproteinase-2 ( TIMP-2 ) to pro-MMP-2 and mature membrane type-1 MMP (MT1-MMP) on the cell surface is required for activation of MMP-2
Sakimoto et al., Jpn J Ophthalmol 2004 (Conjunctival Diseases...) : ( 2 ) Immunohistochemical study : By using the alkaline phosphate-anti-alkaline phosphatase or avidin-biotin complex method, corneal or conjunctival tissue was examined for the presence of MMP-2, MMP-9, and membrane type 1 (MT1)-MMP , which activates MMP-2
Suzuki et al., Mol Cell Biol 2004 (Neoplasms) : In addition, ARK5 expression induced activation of matrix metalloproteinase 2 (MMP-2) and MMP-9 following new expression of membrane type 1 MMP (MT1-MMP) , and the MT1-MMP expression induced by ARK5 was initiated by rapamycin-sensitive signaling
Lafleur et al., J Biol Chem 2006 : Type I collagen ( Col I ) -stimulated matrix metalloproteinase-2 (MMP-2) activation via membrane type 1 MMP (MT1-MMP) involves both a transcriptional increase in MT1-MMP expression and a nontranscriptional response mediated by preexisting MT1-MMP
Taniwaki et al., Cancer Res 2007 (Neoplasms, Experimental) : The membrane type 1-MMP (MT1-MMP) is a highly potent activator of MMP-2 and is expressed in many tumor and stromal cells
Ispanovic et al., Am J Physiol Cell Physiol 2008 : Skeletal muscle microvascular endothelial cells exhibit robust actin stress fibers, low levels of membrane type 1 (MT1)-MMP expression, and minimal MMP-2 activation
Nishida et al., Cancer Res 2008 (Neoplasm Metastasis) : The suggested model for pro-matrix metalloproteinase-2 ( proMMP-2 ) activation by membrane type 1 MMP (MT1-MMP) implicates the complex between MT1-MMP and tissue inhibitor of MMP-2 (TIMP-2) as a receptor for proMMP-2
Sakr et al., Cancer Sci 2010 : GI24, an immunoglobulin superfamily member, has been cloned from a placenta cDNA library as a gene product that promoted activation of matrix metalloproteinase (MMP)-2 mediated by membrane type (MT) 1-MMP
Kazes et al., Kidney Int 1998 : Matrix metalloprotease 2 (MMP2) is secreted in a latent inactive form ( pro-MMP2 ) that is activated on the cell surface by a membrane-type 1 MMP (MT1-MMP) in the presence of the tissue inhibitor of MMP ( TIMP2 )