Gene interactions and pathways from curated databases and text-mining

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CEBPA — SMAD3

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

Text-mined interactions from Literome

Feinberg et al., J Biol Chem 2004 (Arteriosclerosis...) : We demonstrate that the inhibitory effect of Smad3 occurs via a novel antagonistic effect of Smad3 on C/EBP DNA-protein binding and activity
Nerlov et al., Curr Opin Cell Biol 2008 : Finally, interaction with Smad proteins, which are accumulated in the nucleus upon TGFbeta or BMP signaling, may lead to the formation of C/EBP-Smad complexes and activation of Smad-C/EBPbeta coregulated promoters, while at the same time inhibiting other C/EBP dependent transcription
Hein et al., BMC molecular biology 2011 : Thus SMAD3 appears to be a potential link between TGFß1 signaling and C/EBP regulated promoter activity