Gene interactions and pathways from curated databases and text-mining

◀ Back to TNF

CCND1 — TNF

Text-mined interactions from Literome

Ashikawa et al., J Immunol 2002 : Piceatannol abrogated the expression of TNF induced NF-kappaB dependent reporter gene and of matrix metalloprotease-9, cyclooxygenase-2, and cyclin D1
Leclercq et al., Gastroenterology 2003 (Drug-Induced Liver Injury...) : Leptin replacement corrected these defects in ob/ob mice by restoring TNF and IL-6 release and inducing cyclin D1
Takada et al., J Biol Chem 2004 : Flavopiridol also inhibited the expression of the TNF induced NF-kappaB regulated gene products cyclin D1 , cyclooxygenase-2, and matrix metalloproteinase-9
Wang et al., Zhonghua Wai Ke Za Zhi 2005 (Breast Neoplasms) : On the other hand, TNF-alpha inhibited cyclin D(1) expression
Aggarwal et al., Mol Pharmacol 2006 (Neoplasm Metastasis) : Such TNF induced NF-kappaB regulated gene products involved in cellular proliferation [ cyclooxygenase-2 (COX-2), cyclin D1 , and c-myc ], antiapoptosis [ inhibitor of apoptosis protein (IAP)1, IAP2, X-chromosome linked IAP, Bcl-2, Bcl-x ( L ), Bfl-1/A1, TNF receptor associated factor 1, and cellular Fas associated death domain protein-like interleukin-1beta converting enzyme inhibitory protein-like inhibitory protein ], and metastasis ( vascular endothelial growth factor, matrix metalloproteinase-9, and intercellular adhesion molecule-1 ) were also down-regulated by curcumin
Zhang et al., Endocrinology 2007 : Using MEC from p50 null mice, we found that p50 was not required for TNF induced growth nor for up-regulation of cyclin D1 ... These data suggest that in wild-type MEC, TNF stimulates the interaction of bcl3 with p50 and p52, and the binding of p52, as well as RelB, to cyclin D1 promoter kappaB sites, and as a consequence, stimulates the growth of MEC
Radeff-Huang et al., J Biol Chem 2007 (Brain Neoplasms...) : Furthermore, cyclin D expression was increased by TNF-alpha in a SphK- and Akt dependent manner
Ahn et al., Cancer Res 2007 (Skin Neoplasms) : The induction of various antiapoptotic gene products ( MMP-9, cyclin D1 , COX-2, IAP1, IAP2, Bcl-2, cFLIP, and XIAP ) by TNF was also abolished in NQO2-/- cells
Böcker et al., J Mol Med (Berl) 2008 : TNF-alpha led to the upregulated expression of the proliferation associated gene cyclin D1
Higashimoto et al., J Biol Chem 2008 : Activation of Plk1 inhibited TNF induced expression of cyclin D1 ... In cells in which Plk1 was knocked down, TNFalpha increased expression of cyclin D1 and the proportion of cells in the S phase of the cell cycle ... Moreover, we identify Plk1 as a gammaBD kinase, which negatively regulates TNF induced IKK activation and cyclin D1 expression, thereby affecting cell cycle regulation ... Untimely activation of cyclin D1 by TNFalpha can provide a potential mechanism for an involvement of TNFalpha in inflammation induced cancer
Park et al., Biochem Pharmacol 2011 (Inflammation...) : Triptolide also abrogated TNF induced expression of cell survival proteins ( XIAP, Bcl-x ( L ), Bcl-2, survivin, cIAP-1 and cIAP-2 ), cell proliferative proteins ( cyclin D1 , c-myc and cyclooxygenase-2 ), and metastasis proteins ( ICAM-1 and MMP-9 )