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CLU — TNF

Text-mined interactions from Literome

Savković et al., Biochem Biophys Res Commun 2007 (Disease Models, Animal...) : Presence of clusterin reduced NF-kappaB activation and expression of the NF-kappaB target genes TNF-alpha and MOB-1 under cell stress
Falgarone et al., Physiol Genomics 2012 (Arthritis, Rheumatoid...) : Moreover, differential comparison showed that CLU downregulation in RA led to a profound modification of the TNF-a response as three sets of genes emerged : 497 genes modulated by siCLU transfection with TNF stimulation, 356 genes modified because of TNF stimulation only, and 484 genes modulated during TNF stimulation with CLU expression ( e.g., IL-8 and Wnt signaling genes )
Humphreys et al., Biochemistry 1997 : Effects of clusterin overexpression on TNFalpha- and TGFbeta mediated death of L929 cells
Pampfer et al., Development 1997 (Pregnancy in Diabetics) : Tumor necrosis factor-alpha (TNF-alpha) , a cytokine whose synthesis is up-regulated in the diabetic uterus, did not induce nuclear fragmentation nor clusterin expression but increased the incidence of TUNEL positive nuclei
Dejardin et al., Oncogene 1998 (Breast Neoplasms) : Stable transfection of a unresponsive mutated IkappaB-alpha Ser 32-36 expression vector showed that TNF-alpha induced MHC Cl I expression in an NF-kappaB dependent way while IFN-gamma did it independently of any NF-kappaB activation