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DDAH2 — TNF

Text-mined interactions from Literome

Ito et al., Circulation 1999 (Hypercholesterolemia) : Accordingly, we studied the effects of oxidized LDL ( oxLDL ) or tumor necrosis factor-alpha (TNF-alpha) on the accumulation of ADMA by transformed human umbilical vein endothelial cells ( ECV304 ) and on the enzyme dimethylarginine dimethylaminohydrolase ( DDAH ), which degrades ADMA
Jiang et al., Acta Pharmacol Sin 2004 : In cultured ECV304 cells, LDL or ox-LDL markedly increased the level of ADMA and TNF-alpha and potentiated the adhesion of monocytes to endothelial cells, concomitantly with a significantly decrease in the activity of DDAH and serum level of NO