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CBL — RAC3

Text-mined interactions from Literome

Scaife et al., J Cell Sci 2000 : This study therefore identifies a cytoskeletal role for c-Cbl which may involve the regulation of Crk and Rac , and which is dependent on targeting of c-Cbl to actin lamellae and the ability to recruit signalling protein ( s ) associated with its divergent SH2 domain
Feng et al., EMBO J 2004 : The binding of either PAK ( p21 activated kinase ) or Cbl ( Casitas B-lymphoma ) to the SH3 domain of monomeric Cool-2 is necessary for the functional interactions between GDP bound Cdc42 or Rac and the Cool-2 monomer
Miranti et al., Curr Biol 1998 : This pathway may regulate multiple downstream events in hematopoietic cells, including Rac induced lamellipodia formation, tyrosine phosphorylation of Cbl , and activation of JNK, ERK2 and the phosphatidylinositol 3'-kinase regulated kinase Akt