Damle et al., J Immunol 1992
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Stimulation of T cells with coimmobilized anti-TCR-1 and ICAM-2 resulted in the induction of IL-2R ( CD25 ), and anti-Tac ( CD25 ) mAb inhibited this response suggesting the contribution of endogenously synthesized IL-2 during this stimulation
Plaisance et al., Int Immunol 1993
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We have also observed, in these fibroblastic cells, the up-regulation of ICAM-2 expression by IL-2 , both in sparse and dense cultures
Zuckerman et al., J Immunol 1998
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In Th1 clones, activation by ProAd-ICAM induces very transient IL-2 mRNA expression that does not result in detectable IL-2 secretion or T cell proliferation