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ATR — WRN
Protein-Protein interactions - manually collected from original source literature:
Studies that report less than 10 interactions are marked with *
Text-mined interactions from Literome
Lee et al., Hormone research in pædiatrics 2010
(Werner Syndrome) :
Moreover,
WRN is
suppressed by
ATR that is activated by DNA damage, whereas WRN can be induced by ATR elimination
Pichierri et al., Oncogene 2012
:
We also find that
ATR dependent
WRN phosphorylation depends on TopBP1, which is recruited by the 9.1.1 complex in response to replication arrest