Gene interactions and pathways from curated databases and text-mining

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ATR — WRN

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

Text-mined interactions from Literome

Lee et al., Hormone research in pædiatrics 2010 (Werner Syndrome) : Moreover, WRN is suppressed by ATR that is activated by DNA damage, whereas WRN can be induced by ATR elimination
Pichierri et al., Oncogene 2012 : We also find that ATR dependent WRN phosphorylation depends on TopBP1, which is recruited by the 9.1.1 complex in response to replication arrest