Gene interactions and pathways from curated databases and text-mining

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CEL — TNF

Text-mined interactions from Literome

Hildebrandt et al., Blood 2004 (Pneumonia) : Using a lethally irradiated parent -- > F1 mouse IPS model, we showed that 5 weeks after transplantation allo-BMT recipients developed significant lung injury compared with syngeneic controls, which was associated with increased bronchoalveolar lavage (BAL) fluid levels of TNF-alpha, elevated numbers of donor derived TNF-alpha secreting T cells, and increased pulmonary macrophage production of TNF-alpha to lipopolysaccharide (LPS) stimulation
Nyberg et al., Acta Anaesthesiol Scand 2004 (Respiratory Distress Syndrome, Adult) : TNFalpha levels increased in ETX, but not in BAL , animals
Yamanishi et al., J Biochem 2007 : CEL-I , an invertebrate N-acetylgalactosamine-specific C-type lectin, induces TNF-alpha and G-CSF production by mouse macrophage cell line RAW264.7 cells ... In this study, we found that CEL-I induced increased secretion of tumour necrosis factor-alpha (TNF-alpha) and granulocyte colony stimulation factor ( G-CSF ) by mouse macrophage cell line RAW264.7 cells in a dose dependent manner, whereas this cell line was highly resistant to CEL-I cytotoxicity