◀ Back to VCAM1

ITLN1 — VCAM1

Text-mined interactions from Literome

Kazama et al., Eur J Pharmacol 2012 : Western blotting was performed to analyze inflammatory signal transduction in cultured SMCs. Phosphorylation of nuclear factor-?B ( NF-?B ), p38 and JNK, and expression of vascular cell adhesion molecule (VCAM)-1 and cyclooxygenase-2 were not induced by omentin ( 50-300ng/ml, 20min or 24h ) ... In rat isolated thoracic aorta, omentin ( 300ng/ml, 30min ) inhibited TNF-a ( 24h ) -induced VCAM-1 expression ... It is suggested that omentin inhibits TNF-a induced VCAM-1 expression via preventing the activation of p38 and JNK at least in part through inhibition of superoxide production
Zhong et al., Biochem Biophys Res Commun 2012 (MAP Kinase Signaling System) : In the present study, we investigated whether omentin affected the expression of intracellular adhesion molecule-1 ( ICAM-1 ) and vascular cell adhesion molecule-1 ( VCAM-1 ) in tumor necrosis factor-a (TNF-a) induced human umbilical vein endothelial cells ( HUVECs ) ... Omentin , NF-kB inhibitor ( BAY11-7082 ) and ERK inhibitor ( PD98059 ) reduced the up-regulation of ICAM-1 and VCAM-1 induced by TNF-a