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MYLIP — TGFB1
Text-mined interactions from Literome
Sun et al., Nucleic Acids Res 2008
:
In this study, we found that
miR-24 was upregulated during myoblast differentiation and could be
inhibited by
TGF-beta1 ... Using both a reporter assay and Northern blot analysis, we showed that
TGF-beta1 repressed
miR-24 transcription which was dependent on the presence of Smad3 and a Smads binding site in the promoter region of miR-24
Gregory et al., Nat Cell Biol 2008
(Breast Neoplasms...) :
We found that all five members of the microRNA-200 family ( miR-200a, miR-200b, miR-200c, miR-141 and miR-429 ) and
miR-205 were markedly downregulated in cells that had undergone EMT in
response to
transforming growth factor ( TGF ) -beta or to ectopic expression of the protein tyrosine phosphatase Pez
Huang et al., Int J Cancer 2008
(Carcinoma, Hepatocellular...) :
Upregulation of
miR-23a approximately 27a approximately 24 decreases
transforming growth factor-beta induced tumor-suppressive activities in human hepatocellular carcinoma cells
Du et al., FEBS Lett 2010
:
In this study, we examined the miRNA profile of HK-2 cells and found that high
glucose/TGF-beta1 induced significant down-regulation of
miR-29a
Jurkin et al., J Immunol 2010
(Bacterial Infections) :
Interestingly, constitutive high
miR-146a expression in LCs is induced by the transcription factor PU.1 in
response to
TGF-beta1 , a key microenvironmental signal for epidermal LC differentiation
Liu et al., J Exp Med 2010
(Idiopathic Pulmonary Fibrosis...) :
TGF-beta1 , a central pathological mediator of fibrotic diseases,
enhanced miR-21 expression in primary pulmonary fibroblasts
Roderburg et al., Hepatology 2011
(Carbon Tetrachloride Poisoning...) :
On a cellular level, down-regulation of
miR-29 in murine hepatic stellate cells ( HSCs ) was
mediated by
transforming growth factor beta ( TGF-ß ) as well as inflammatory signals, namely, lipopolysaccharide (LPS) and nuclear factor kappa B ( NF-?B )
Li et al., J Cell Biochem 2012
:
MTT assay and Western blot showed that
miR-17-92 inhibited
TGFB1 induced proliferation inhibition and collagen synthesis in PMCs by decreasing TGFBR2, SMAD2, and SMAD4 protein level