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PTX3 — RAC2

Text-mined interactions from Literome

Katsube et al., J Leukoc Biol 2008 : NSC23766 ( Rac inhibitor ) and pertussis toxin ( PTX ) suppressed calpain inhibitor induced phosphorylation of distinct signaling molecules ( PAK, c-Raf, MEK1/2, ERK, MKK3/6, p38, JNK, and Akt ) as well as cell migration, suggesting that the PTX-sensitive G protein and Rac axis may be a possible key target of calpain inhibitors
Noma et al., Immunology 2009 : NSC23766 ( Rac inhibitor ) and pertussis toxin ( PTX ) suppressed calpain inhibitor induced phosphorylation of distinct signalling molecules ( PAK, ERK, p38, JNK and Akt ) as well as cell migration, suggesting that the PTX-sensitive G protein and Rac axis may be a possible key target of calpain inhibitors
Nishida et al., J Biol Chem 2010 : PTX induced biphasic increases in Rac activity, and the Rac activation in a late but not an early phase was suppressed by IL-1beta siRNA, suggesting that IL-1beta induced Rac activation contributes to the amplification of Rac dependent signaling induced by PTX ... Furthermore, inhibition of TLR4 ( Toll-like receptor 4 ) abolished PTX induced Rac activation and enhancement of AT1R function