Gene interactions and pathways from curated databases and text-mining

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ALB — ECM2

Text-mined interactions from Literome

Brill et al., Eur J Cell Biol 2002 : Adult hepatocytes ECM strongly induced expression of both albumin and HNF-4 in adult hepatocytes
Baricos et al., Experimental biology and medicine (Maywood, N.J.) 2003 : Taken together, these results document the importance of tPA versus uPA in renal plasmin production and indicate that in contrast to elevated glucose, glycated albumin may contribute to ECM accumulation in diabetic nephropathy
Stephan et al., Am J Nephrol 2004 : We demonstrate that human albumin stimulates the accumulation of ECM proteins by proximal tubular epithelial cells through a post-transcriptional mechanism ... Taken together, our data suggest that ECM protein accumulation in response to albumin resulted partly from inhibition of ECM degradation ... Addition of transforming growth factor beta ( TGF-beta ) -specific neutralizing antibody failed to alter ECM protein levels after albumin treatment, indicating that the albumin induced increase in ECM is TGF-beta independent
Li et al., Biochem Biophys Res Commun 2010 (Diabetic Nephropathies) : Therefore, in the present studies, we determined the mechanisms by which glycated albumin activates NADPH oxidase in primary rat mesangial cells and its contribution to glycated albumin induced TGF-beta expression and extracellular matrix protein production