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DACH1 — JUN

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

• IRef Biogrid Interaction: DACH1 — JUN (physical association, affinity chromatography technology) Wu et al., Mol Biol Cell 2007*
• IRef Biogrid Interaction: DACH1 — JUN (direct interaction, two hybrid) Wu et al., Mol Biol Cell 2007*
• IRef Biogrid Interaction: DACH1 — JUN (physical association, affinity chromatography technology) Wu et al., Mol Cell Biol 2006*

Text-mined interactions from Literome

Wu et al., J Biol Chem 2003 : DACH1 repressed TGF-beta induction of AP-1 and Smad signaling in gene reporter assays and repressed endogenous TGF-beta-responsive genes by microarray analyses ... NCoR enhanced DACH1 repression, and the repression of TGF-beta induced AP-1 or Smad signaling by DACH1 required the DACH1 DS domain
Wu et al., Mol Biol Cell 2007 : DACH1 coprecipitated the histone deacetylase proteins ( HDAC1, HDAC2, and NCoR ), providing a mechanism by which DACH1 represses c-Jun activity through the conserved delta domain