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FGF18 — VEGFA
Pathways - manually collected, often from reviews:
Text-mined interactions from Literome
Wu et al., J Biol Chem 2000
:
However, blockade of PKC diminished thymidine incorporation into DNA
induced by
VEGF but not
FGF or EGF
Saadeh et al., Endocrinology 2000
:
Furthermore,
FGF-2 induced dose dependent increases in
VEGF protein levels ( P < 0.01 ) ... In summary,
FGF-2 induced
VEGF expression by osteoblastic cells is a dose dependent event that may be independent of concomitant FGF-2 induced modulation of TGFbeta activity
Hajitou et al., Breast Cancer Res Treat 2000
(Breast Neoplasms) :
Remarkably,
FGF-4 but not FGF-3,
stimulated the secretion of
vascular endothelial growth factor ( VEGF165 ) without altering the steady-state level of its mRNA, suggesting a possible regulation of VEGF synthesis at the translational level in MCF7 cells
Xu et al., J Thorac Cardiovasc Surg 2001
(Acute Disease...) :
This study suggests that acute myocardial ischemia in patients results in increased expression of vascular endothelial growth factor but not
fibroblast growth factor and that the functional activity of
vascular endothelial growth factor receptors and that of other growth factors may be
impaired
Scapini et al., J Immunol 2002
:
Remarkably, affinity purified angiostatin kringle 1-3 fragments generated by neutrophils inhibited basic fibroblast growth factor plus vascular endothelial growth factor induced endothelial cell proliferation in vitro, and both
vascular endothelial growth factor induced angiogenesis in the matrigel plug assay and
fibroblast growth factor induced angiogenesis in the chick embryo chorioallantoic membrane assay, in vivo
Heryanto et al., Reproduction 2003
:
These results demonstrate that endometrial angiogenesis after acute oestrogen treatment is primarily mediated by
VEGF , but that under the influence of combined oestrogen and progesterone,
FGF and PDGF are also probably
involved
Hesling et al., J Invest Dermatol 2004
(Melanoma...) :
We also demonstrate that : ( 1 ) among the major pro-angiogenic genes,
FGF-2 was not increased before or after irradiation and
vascular endothelial growth factor strongly
inhibited after irradiation ; ( 2 ) expression of two important metalloproteinases, matrix metalloproteinase 2 and 9, involved in melanoma metastasis were decreased before and after irradiation ; ( 3 ) expression of their major inhibitor, tissue inhibitor of metalloproteinase, was mainly upregulated ; and ( 4 ) that invasion of BRCA1 downregulated cells was modified
Horiguchi et al., Endocrine 2004
:
Basic
FGF and EGF did not modulate changes in VEGF-A mRNA levels after 4 and 24 h of treatment, but EGF
increased VEGF-A significantly ( p < 0.05 ) after 96 h of treatment
Laschke et al., Hum Reprod 2006
(Endometriosis...) :
Combined inhibition of vascular endothelial growth factor ( VEGF ),
fibroblast growth factor and platelet derived growth factor, but not
inhibition of
VEGF alone, effectively suppresses angiogenesis and vessel maturation in endometriotic lesions
Shi et al., Pathology 2007
(Breast Neoplasms...) :
Basic
FGF augments hypoxia
induced HIF-1-alpha expression and
VEGF release in T47D breast cancer cells
Murakami et al., J Clin Invest 2011
(Ischemia) :
FGF dependent regulation of
VEGF receptor 2 expression in mice