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HOXA9 — VEGFA
Text-mined interactions from Literome
Rössig et al., J Exp Med 2005
(Ischemia) :
Knockdown and overexpression studies revealed that
HoxA9 acts as a master switch to
regulate the expression of prototypical endothelial committed genes such as endothelial nitric oxide synthase,
VEGF-R2 , and VE-cadherin, and mediates the shear stress induced maturation of endothelial cells
Kaushansky et al., Ann N Y Acad Sci 2005
:
We found that TPO enhances the transcription of HoxB4,
induces the nuclear localization of
HoxA9 , and upregulates
VEGF expression by reducing the ubiquination of hypoxia inducible factor