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MIPEP — TLR2

Text-mined interactions from Literome

Lucas et al., J Immunol 2003 : TLR ligands induced early and sustained secretion of TNF-alpha, macrophage-inflammatory protein (MIP) 1alpha and MIP-2 with later secretion of IL-10, IL-12, and TGF-beta1 ; apoptotic cells alone stimulated late TGF-beta1 secretion only
Heggelund et al., Clin Exp Immunol 2004 (HIV Infections) : Our main findings were, with similar qualitative patterns in both healthy controls and HIV infected patients : ( 1 ) TLR2 stimulation induced up-regulation of several chemokines at the mRNA level as well as increased protein levels of macrophage inflammatory protein (MIP)-1alpha , interleukin (IL)-8 and regulated on activation, normal T cell expressed and secreted ( RANTES ) ; ( 2 ) TLR2 stimulation induced enhanced protein expression of CCR5 ( a receptor for MIP-1alpha and RANTES ) on monocytes ; ( 3 ) In vitro stimulation with RANTES induced release of MIP-1alpha, MCP-1, IL-8 and interferon-gamma from PBMC
Peña-Cruz et al., J Invest Dermatol 2010 : PD-1 engagement on iLCs reduced IL-6 and macrophage inflammatory protein (MIP)-1alpha cytokine production in response to TLR2 signals but had no effect on LC maturation
Schwacha et al., International journal of clinical and experimental medicine 2012 : TLR2 induced KC and MIP-1ß production was greater in the burn group at 3-7 days post-injury, whereas IL-6, IL-10, KC and MIP-1ß were greater for TLR4 induced activation after burn