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CSK — IL6
Text-mined interactions from Literome
Davey et al., Microvasc Res 2006
:
Endothelial cells from choroid demonstrated enhanced release of
IL-6 in response to MDP, and synergy was
observed following treatment with MDP and either
Pam3CSK4 or LPS
Rydberg et al., Immunology 2009
(Carcinoma, Squamous Cell...) :
Poly ( I:C )
induced a small increase in IL-1beta,
IL-6 and IL-8 production in HNECs, while Pam ( 3 )
CSK ( 4 ) increased viability
Into et al., Cell Immunol 2010
(Bacterial Infections...) :
LL-37 modestly attenuated the expression of
IL6 and IL8
induced by the TLR2/TLR1 ligand Pam ( 3 )
CSK ( 4 ), but did not affect the expression induced by the TLR2/TLR6 ligand MALP-2
Ultaigh et al., Arthritis Res Ther 2011
(Arthritis, Rheumatoid) :
OPN301 significantly decreased
Pam3CSK4 induced cytokine production of tumour necrosis factor alpha ( TNF-a ), IL-1ß,
IL-6 , interferon ( IFN ) -? and IL-8 compared to IgG control in RA PBMCs and SFMCs cultures ( all P < 0.05 )
Caraş et al., Roum Arch Microbiol Immunol 2011
:
Unexpectedly, treatment with anti-LR2 blocking antibody inhibited only
IL-6 production
induced by
Pam3CSK4 while the level of TNF-alpha was unchanged
Li et al., Inflammation 2012
(Endotoxemia) :
We found that in vitro LPS and
Pam3CSK4 induced TNF-a, and
IL-6 production are decreased in macrophages from GS/GS mice compared with WT mice ( p? < ?0.05 )
Morandini et al., J Periodontol 2013
(Inflammation) :
Knockdown of TLR2 decreased
IL-6 and IL-8 in
response to P. gingivalis LPS, or
Pam2CSK4 and Pam3CSK4, in a similar manner in both fibroblasts subpopulations
Yao et al., Eur J Immunol 2012
(Inflammation) :
Here, we report that ATP enhanced murine IEC production of KC,
IL-6 , TGF-ß, and thymic stromal lymphopoietin in
response to TLR1/2 stimulation by Pam ( 3 )
CSK ( 4 ) ( PAM )
Lee et al., Arterioscler Thromb Vasc Biol 2012
(Atherosclerosis) :
Moreover, cAMP response element binding protein small interfering RNA inhibited
pam3CSK4 induced
IL-6 production and VSMC migration ... Additionally, Rac1 small interfering RNA inhibited
pam3CSK4 induced VSMC migration but not
IL-6 production