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CD4 — WAS
Text-mined interactions from Literome
Marangoni et al., J Exp Med 2007
(Wiskott-Aldrich Syndrome) :
WASP regulates suppressor activity of human and murine
CD4 ( + ) CD25 ( + ) FOXP3 ( + ) natural regulatory T cells
Bouma et al., Blood 2007
(Wiskott-Aldrich Syndrome) :
At low doses of antigen,
activation of preprimed wild-type
CD4 ( + ) T lymphocytes by
WAS KO DCs in vitro was also abrogated, suggesting that there is a threshold dependent impairment even if successful DC-T cell colocalization is achieved
Lafouresse et al., Immunology 2012
:
Our data therefore indicate that
WASP controls
CD4 ( + ) T-cell motility upon APC encounter by regulating lymphocyte function associated antigen 1 spatial distribution