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ERBB2 — ITGA2

Text-mined interactions from Literome

Yoon et al., Cancer Res 2006 (Breast Neoplasms...) : In summary, we propose a novel mechanism for ErbB2 up-regulation and Ras activation in serum depleted breast cancer cells ; integrin alpha(6)beta ( 4 ) regulates the expression of ErbB2 and the subsequent phosphorylation of EGFR and activation of Ras
Ye et al., Mol Cell Biol 1996 : These data suggest that in luminal epithelial cells and the breast cancers which develop from them, the Erb-B2 proto-oncogene signaling leads to inhibition of ( alpha)2(beta)1-integrin gene expression and could contribute to the disruption of tissue architecture seen in breast cancers