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BAX — LEP
Text-mined interactions from Literome
Bruno et al., J Immunol 2005
(MAP Kinase Signaling System) :
Moreover,
leptin delayed the cleavage of Bid and
Bax , the mitochondrial release of cytochrome c and second mitochondria derived activator of caspase, as well as the activation of both caspase-8 and caspase-3 in these cells
Conus et al., J Allergy Clin Immunol 2005
(MAP Kinase Signaling System) :
Leptin delayed the cleavage of
Bax , as well as the mitochondrial release of cytochrome c and second mitochondria derived activator of caspase, suggesting that it blocks proapoptotic pathways proximal to mitochondria in eosinophils
Sirotkin et al., Physiol Res 2008
:
It was observed that
leptin stimulated in a dose dependent manner the accumulation of PCNA ( at doses 1-100 ng/ml ), cyclin B1 ( at doses 10 or 100 ng/ml ),
Bax ( at doses 10 or 100 ng/ml ) and PKA ( at doses 1-100 ng/ml ) in cultured human ovarian cells
Shin et al., J Cell Physiol 2009
(Anoxia) :
Leptin reduced HR-induced translocation of the pro-apoptotic protein
Bax to the mitochondrial membrane, which provides a mechanism to explain its protective effect
Rucinski et al., Int J Mol Med 2010
:
In comparison with intact rats, expression levels of ppGHREL,
BAX , JUN-B and JUN-C genes were notably higher in regenerating adrenals, and neither GHREL nor
OBS infusion
affected these levels