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IL15 — IRF1

Text-mined interactions from Literome

Coccia et al., J Biol Chem 1999 : No significant differences of IRF-1 mRNA expression were found in established Th1 and Th2 cells ; however, interleukin 12 (IL-12) induced a strong up-regulation of IRF-1 transcripts in Th1 but not in Th2 cells
De Creus et al., J Immunol 2002 (Leukopenia) : In this study, the role of IL-15 and its regulation by the transcription factor IFN regulatory factor-1 (IRF-1) in murine V gamma 3 T cell development and activity is assessed
Ashkar et al., J Immunol 2003 : IL-15 mRNA expression at implantation sites of IRF-1 ( -/- ) and C57BL/6 was similar, suggesting that, unlike in bone marrow and spleen, IRF-1 does not regulate IL-15 in the pregnant uterus
Ogasawara et al., Nature 1998 : We also show that IRF-1 ( -/- ) bone-marrow cells can generate functional NK cells when cultured with the cytokine interleukin-15 and that the interleukin-15 gene is transcriptionally regulated by IRF-1
Ohteki et al., J Exp Med 1998 : These data indicate that IRF-1 regulates IL-15 gene expression, which may control the development of NK1+T cells, NK cells, and CD8-alpha/alpha+ IELs