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UCSC Genome Browser Gene Interaction Graph
Gene interactions and pathways from curated databases and text-mining

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IRF1 — TP53

Text-mined interactions from Literome

Yu et al., Exp Mol Med 2004 (Carcinoma, Renal Cell...) : Up-regulation of p21WAF1 and IRF-1 expression is transcriptional, but independent of p53
Jiang et al., J Exp Clin Cancer Res 2007 (Carcinoma, Hepatocellular...) : Overexpression of IRF-1 augmented the combined interferon-gamma/adriamycin induced p53 accumulation
Pang et al., Cell cycle (Georgetown, Tex.) 2011 : TLR3-IRF1 or ATM dependent signaling to p53 is defective in p21-null cells and complementation of the p21 gene in p21-null cancer cells restores the p53 transcriptional response
Fritsche et al., Mol Cell Endocrinol 1998 : p53 repressed the prolactin induction of the Stat5 mediated transcription of the beta-casein promoter-luciferase reporter gene, but did not affect IFN-gamma induced, Stat1 dependent transcription of the IRF-1 promoter