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UCSC Genome Browser Gene Interaction Graph
Gene interactions and pathways from curated databases and text-mining

◀ Back to EIF4G3

EIF4A1 — EIF4G3

Pathways - manually collected, often from reviews:

  • BioCarta internal ribosome entry pathway: eIF-4G/eIF3/EIF-4A complex (EIF4G1-EIF4G2-EIF4G3-EIF3S10-EIF4A1) → eIF-4G/eIF-4E/PTB complex (EIF4G1-EIF4G2-EIF4G3-EIF4E-PTBP1_PTBP2) (translational initiation, activates)
  • BioCarta internal ribosome entry pathway: eIF-4G/eIF-4E/PTB complex (EIF4G1-EIF4G2-EIF4G3-EIF4E-PTBP1_PTBP2) → eIF-4G/eIF3/EIF-4A complex (EIF4G1-EIF4G2-EIF4G3-EIF3S10-EIF4A1) (modification, collaborate)
  • BioCarta internal ribosome entry pathway: eIF-4G/eIF-4E/PTB complex (EIF4G1-EIF4G2-EIF4G3-EIF4E-PTBP1_PTBP2) → c-Myc mRNA/eIF-4G (dimer)/eIF-3/eIF-4E/eIF-4A/PTB complex (EIF4A1-EIF4E-EIF3S10-EIF4G1-EIF4G2-EIF4G3-PTBP1_PTBP2) (modification, collaborate)
  • BioCarta internal ribosome entry pathway: eIF-4G/eIF3/EIF-4A complex (EIF4G1-EIF4G2-EIF4G3-EIF3S10-EIF4A1) → c-Myc mRNA/eIF-4G (dimer)/eIF-3/eIF-4E/eIF-4A/PTB complex (EIF4A1-EIF4E-EIF3S10-EIF4G1-EIF4G2-EIF4G3-PTBP1_PTBP2) (modification, collaborate)
  • BioCarta internal ribosome entry pathway: Active caspases (CASP5/CASP3/CASP4/CASP8/CASP1/CASP7/CASP6/CASP2/CASP9/CASP10) → eIF-4G/eIF3/EIF-4A complex (EIF4G1-EIF4G2-EIF4G3-EIF3S10-EIF4A1) (modification, activates)
  • BioCarta internal ribosome entry pathway: Active caspases (CASP5/CASP3/CASP4/CASP8/CASP1/CASP7/CASP6/CASP2/CASP9/CASP10) → c-Myc mRNA/eIF-4G (dimer)/eIF-3/eIF-4E/eIF-4A/PTB complex (EIF4A1-EIF4E-EIF3S10-EIF4G1-EIF4G2-EIF4G3-PTBP1_PTBP2) (modification, activates)
  • BioCarta internal ribosome entry pathway: eIF-4G/eIF-4E/PTB complex (EIF4G1-EIF4G2-EIF4G3-EIF4E-PTBP1_PTBP2) → eIF-4G/eIF3/EIF-4A complex (EIF4G1-EIF4G2-EIF4G3-EIF3S10-EIF4A1) (modification, collaborate)
  • BioCarta internal ribosome entry pathway: eIF-4G/eIF-4E/PTB complex (EIF4G1-EIF4G2-EIF4G3-EIF4E-PTBP1_PTBP2) → c-Myc mRNA/eIF-4G (dimer)/eIF-3/eIF-4E/eIF-4A/PTB complex (EIF4A1-EIF4E-EIF3S10-EIF4G1-EIF4G2-EIF4G3-PTBP1_PTBP2) (modification, collaborate)
  • BioCarta internal ribosome entry pathway: eIF-4G/eIF3/EIF-4A complex (EIF4G1-EIF4G2-EIF4G3-EIF3S10-EIF4A1) → c-Myc mRNA/eIF-4G (dimer)/eIF-3/eIF-4E/eIF-4A/PTB complex (EIF4A1-EIF4E-EIF3S10-EIF4G1-EIF4G2-EIF4G3-PTBP1_PTBP2) (modification, collaborate)
  • BioCarta eukaryotic protein translation: 40s Ribosome subunit/RNA strand complex () → 48s Ribosome subunit complex (EIF3S10-EIF2S1-EIF2S2-EIF2S3-EIF4A1-EIF4A2-EIF4G1-EIF4G2-EIF4G3-EIF4E) (modification, collaborate)
  • BioCarta eukaryotic protein translation: eIF3 (EIF3S10) → 48s Ribosome subunit complex (EIF3S10-EIF2S1-EIF2S2-EIF2S3-EIF4A1-EIF4A2-EIF4G1-EIF4G2-EIF4G3-EIF4E) (modification, collaborate)
  • BioCarta eukaryotic protein translation: eIF1 (EIF1) → 48s Ribosome subunit complex (EIF3S10-EIF2S1-EIF2S2-EIF2S3-EIF4A1-EIF4A2-EIF4G1-EIF4G2-EIF4G3-EIF4E) (modification, activates)
  • BioCarta eukaryotic protein translation: 48s Ribosome subunit complex (EIF3S10-EIF2S1-EIF2S2-EIF2S3-EIF4A1-EIF4A2-EIF4G1-EIF4G2-EIF4G3-EIF4E) → EIF-2 complex (EIF2S1-EIF2S2-EIF2S3) (modification, collaborate)
  • BioCarta internal ribosome entry pathway: PTB (PTBP1/PTBP2) → c-Myc mRNA/eIF-4G (dimer)/eIF-3/eIF-4E/eIF-4A/PTB complex (EIF4A1-EIF4E-EIF3S10-EIF4G1-EIF4G2-EIF4G3-PTBP1_PTBP2) (modification, collaborate)
  • BioCarta internal ribosome entry pathway: eIF3 (EIF3S10) → c-Myc mRNA/eIF-4G (dimer)/eIF-3/eIF-4E/eIF-4A/PTB complex (EIF4A1-EIF4E-EIF3S10-EIF4G1-EIF4G2-EIF4G3-PTBP1_PTBP2) (modification, collaborate)
  • BioCarta internal ribosome entry pathway: c-Myc mRNA/eIF-4G (dimer)/eIF-3/eIF-4E/eIF-4A/PTB complex (EIF4A1-EIF4E-EIF3S10-EIF4G1-EIF4G2-EIF4G3-PTBP1_PTBP2) → EIF-4E (EIF4E) (modification, collaborate)
  • BioCarta internal ribosome entry pathway: c-Myc mRNA/eIF-4G (dimer)/eIF-3/eIF-4E/eIF-4A/PTB complex (EIF4A1-EIF4E-EIF3S10-EIF4G1-EIF4G2-EIF4G3-PTBP1_PTBP2) → EIF-4A (EIF4A1) (modification, collaborate)
  • BioCarta internal ribosome entry pathway: c-Myc mRNA/eIF-4G (dimer)/eIF-3/eIF-4E/eIF-4A/PTB complex (EIF4A1-EIF4E-EIF3S10-EIF4G1-EIF4G2-EIF4G3-PTBP1_PTBP2) → eIF-4G (dimer) complex (EIF4G1-EIF4G2-EIF4G3) (modification, collaborate)
  • BioCarta internal ribosome entry pathway: EIF-4A (EIF4A1) → eIF-4G (dimer) complex (EIF4G1-EIF4G2-EIF4G3) (modification, collaborate)
  • BioCarta eukaryotic protein translation: 43s Ribosome subunit complex (EIF3S10-EIF2S1-EIF2S2-EIF2S3) → 48s Ribosome subunit complex (EIF3S10-EIF2S1-EIF2S2-EIF2S3-EIF4A1-EIF4A2-EIF4G1-EIF4G2-EIF4G3-EIF4E) (modification, collaborate)
  • BioCarta eukaryotic protein translation: 43s Ribosome subunit complex (EIF3S10-EIF2S1-EIF2S2-EIF2S3) → eIF4F/mRNA complex (EIF4A1-EIF4A2-EIF4G1-EIF4G2-EIF4G3-EIF4E) (modification, collaborate)
  • BioCarta eukaryotic protein translation: 48s Ribosome subunit complex (EIF3S10-EIF2S1-EIF2S2-EIF2S3-EIF4A1-EIF4A2-EIF4G1-EIF4G2-EIF4G3-EIF4E) → eIF4F/mRNA complex (EIF4A1-EIF4A2-EIF4G1-EIF4G2-EIF4G3-EIF4E) (modification, collaborate)
  • KEGG RNA transport: EIF4G1/EIF4G2/EIF4G3 → EIF4A1/EIF4A2 (protein-protein, binding/association)
  • Reactome Reaction: EIF4A1 → EIF4G3 (direct_complex) Okumura et al., Genes Dev 2007

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *