Rushworth et al., Transplantation 2001
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Human CD154 induces activation of porcine endothelial cells and up-regulation of MHC class II expression
Termeer et al., J Leukoc Biol 2001
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In this system, addition of anti-CD44s mAbs abrogated DC-cluster formation, thereby inhibiting further maturation, as shown by a reduced TNF-alpha production and inhibition of CD154 induced MHC class II up-regulation
Rushworth et al., Transplantation 2002
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We have previously shown that binding of human CD154 expressed on the Jurkat D1.1 cell line to porcine CD40 on pig aortic endothelial cells ( PAECs ) can lead to up-regulation of vascular cell adhesion molecule (VCAM)-1 and MHC class II