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TLR3 — UNC93B1

Pathways - manually collected, often from reviews:

• Reactome Reaction: TLR3 → UNC93B1 (reaction) Tabeta et al., Nat Immunol 2006*, Casrouge et al., Science 2006*, Brinkmann et al., J Cell Biol 2007*, Koehn et al., Hum Immunol 2007*, Kim et al., Nature 2008*, Fukui et al., J Exp Med 2009*, Qi et al., J Biol Chem 2010*, Itoh et al., PloS one 2011*
• Reactome Reaction: TLR3 → UNC93B1 (direct_complex) Tabeta et al., Nat Immunol 2006*, Casrouge et al., Science 2006*, Brinkmann et al., J Cell Biol 2007*, Koehn et al., Hum Immunol 2007*, Kim et al., Nature 2008*, Chockalingam et al., Immunol Cell Biol 2009*, Fukui et al., J Exp Med 2009*, Qi et al., J Biol Chem 2010*, Ewald et al., J Exp Med 2011, Itoh et al., PloS one 2011*

Text-mined interactions from Literome

Koehn et al., Hum Immunol 2007 : Interestingly, UNC-93B itself is specifically induced by TLR3 signaling in monocyte derived dendritic cells and macrophages
Bustamante et al., Curr Opin Immunol 2008 (Genetic Diseases, Inborn...) : Mutations in TLR3 and UNC93B1 impair TLR3 responses and confer a predisposition to herpes simplex encephalitis
Pifer et al., J Biol Chem 2011 (Toxoplasmosis, Animal) : UNC93B1 is essential for TLR11 activation and IL-12 dependent host resistance to Toxoplasma gondii