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KISS1 — MMP9

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

• IRef Hprd Interaction: MMP9 — KISS1 (in vivo) Takino et al., Oncogene 2003*
• IRef Hprd Interaction: MMP9 — KISS1 (in vitro) Takino et al., Oncogene 2003*

Text-mined interactions from Literome

Yan et al., J Biol Chem 2001 (Neoplasm Invasiveness) : KiSS-1 represses 92-kDa type IV collagenase expression by down regulating NF-kappa B binding to the promoter as a consequence of Ikappa Balpha -induced block of p65/p50 nuclear translocation ... However, NF-kappaB binding to the MMP-9 promoter required for expression of this collagenase was reduced by KiSS-1 expression ... Thus, KiSS-1 diminishes MMP-9 expression by effecting reduced NF-kappaB binding to the promoter
Lee et al., Oncol Res 2009 (MAP Kinase Signaling System...) : Kiss-1 suppresses MMP-9 expression by activating p38 MAP kinase in human stomach cancer