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ICAM1 — JAK2
Text-mined interactions from Literome
Zhu et al., J Biol Chem 2003
(Inflammation) :
Immunoprecipitation and Western blotting showed glycolipids Ley-6, H-5-2, or the glucose analog H-2g quickly activated human microvascular endothelial cell line-1 ( HMEC-1 ) Janus kinase 2 (JAK2) and that the
JAK2 inhibitor, AG-490, completely
inhibited HMVEC
ICAM-1 expression and HL-60 adhesion to HMEC-1s
Chang et al., Mol Pharmacol 2004
:
In addition,
ICAM-1 promoter activity induced by IFN-gamma, but not that induced by TPA, was
inhibited by the dominant negative JAK1 and
JAK2 mutants