Gene interactions and pathways from curated databases and text-mining

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HSPG2 — NOS3

Text-mined interactions from Literome

Alvarez de Sotomayor et al., J Vasc Res 2007 (Hypertension) : Only PLC increased eNOS protein expression in SHR
de Sotomayor et al., Free radical research 2007 (Hypertension) : PLC treatment augmented eNOS expression in SHR. Surprisingly, LC increased [ image omitted ] produced by aorta from WKY and thus diminished NO and damaged endothelial function
Chung et al., Exp Mol Med 2012 : A phospholipase C (PLC) inhibitor blocked the increases in intracellular Ca ( 2+ ) levels, AMPK dependent eNOS phosphorylation, and NO production, but not Akt activation, in syringaresinol- treated endothelial cells