Gene interactions and pathways from curated databases and text-mining

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CD8A — ITK

Text-mined interactions from Literome

Dubois et al., Proc Natl Acad Sci U S A 2006 : Thus, whereas ITK dependent CD44 ( lo ) CD122 ( lo ) CD8 ( + ) T cells appear to represent conventional CD8 ( + ) T cells, IL-15 dependent CD44 ( hi ) CD122 ( hi ) CD8 ( + ) T cells may have functions in both adaptive and innate immunity
Huang et al., J Immunol 2013 : Innate memory phenotype (IMP) CD8 ( + ) T cells are nonconventional aß T cells exhibiting features of innate immune cells and are significantly increased in the absence of ITK