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FGF9 — NANOS2
Text-mined interactions from Literome
Faure et al., Ocul Immunol Inflamm 1999
:
We have attempted to describe and compare the
effect of
fibroblast growth factor ( FGF ) and transforming growth factor beta ( TGFbeta ) on
NOS-II mRNA level in three different cell species : rat, bovine, and human
Barrios et al., J Cell Sci 2010
:
Opposing
effects of retinoic acid and
FGF9 on
Nanos2 expression and meiotic entry of mouse germ cells ... Interestingly,
FGF9 , a growth factor crucial for sex differentiation and survival of fetal gonocytes,
upregulates levels of
NANOS2 in both male and female primordial germ cells ( PGCs ) and in premeiotic spermatogonia ... This effect was paralleled by an impairment of meiotic entry, suggesting that
FGF9 acts as an inhibitor of meiosis through the upregulation of
Nanos2