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IKBKB — MLN
Text-mined interactions from Literome
Zhang et al., Nat Med 2013
(Neoplasm Metastasis...) :
Pretreatment of mice with
MLN120B , a selective
inhibitor of
IKK-2 , resulted in suppression of neutrophil infiltration to the lung tissues and reduction of MPO activity
Rauert-Wunderlich et al., PloS one 2013
(Multiple Myeloma) :
Here, we comparatively tested NF?B activity abrogation through TPCA-1 ( an
IKK2 inhibitor ), BAY 11-7082 ( an IKK inhibitor poorly selective for IKK1 and IKK2 ), and
MLN4924 ( an NEDD8 activating enzyme (NAE)-inhibitor ), and analyzed their anti-MM activity