Gene interactions and pathways from curated databases and text-mining

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IKBKB — MLN

Text-mined interactions from Literome

Zhang et al., Nat Med 2013 (Neoplasm Metastasis...) : Pretreatment of mice with MLN120B , a selective inhibitor of IKK-2 , resulted in suppression of neutrophil infiltration to the lung tissues and reduction of MPO activity
Rauert-Wunderlich et al., PloS one 2013 (Multiple Myeloma) : Here, we comparatively tested NF?B activity abrogation through TPCA-1 ( an IKK2 inhibitor ), BAY 11-7082 ( an IKK inhibitor poorly selective for IKK1 and IKK2 ), and MLN4924 ( an NEDD8 activating enzyme (NAE)-inhibitor ), and analyzed their anti-MM activity