Gene interactions and pathways from curated databases and text-mining

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SMARCC1 — SMARCE1

Pathways - manually collected, often from reviews:

  • BioCarta chromatin remodeling by hswi/snf atp-dependent complexes: glucocorticoid/glucocorticoid receptor/glucocorticoid/glucocorticoid receptor complex (NR3C1) → hSWI/SNF complex (SMARCA4-SMARCD1-ARID1A-SMARCC1-SMARCC2-SMARCB1-SMARCE1-ACTB) (modification, collaborate)
  • BioCarta chromatin remodeling by hswi/snf atp-dependent complexes: hSWI/SNF complex (SMARCA4-SMARCD1-ARID1A-SMARCC1-SMARCC2-SMARCB1-SMARCE1-ACTB) → glucocorticoid/glucocorticoid receptor/glucocorticoid/glucocorticoid receptor/hSWI/SNF complex (NR3C1-NF1) (modification, collaborate)
  • BioCarta the information processing pathway at the ifn beta enhancer: IFN-beta nucleosome complex (RELA-ATF2-IRF5_IRF1_IRF3_IRF6_IRF7_IRF4_IRF2-JUN-HMGB1-PCAF-CREBBP-SMARCA4-SMARCD1-ARID1A-SMARCC1-SMARCC2-SMARCB1-SMARCE1-ACTB) → RELA/p50/ATF-2/IRF/c-JUN/HMG1/PCAF/CBP/hSWI/SNF complex (RELA-ATF2-IRF5_IRF1_IRF3_IRF6_IRF7_IRF4_IRF2-JUN-HMGB1-PCAF-CREBBP-SMARCA4-SMARCD1-ARID1A-SMARCC1-SMARCC2-SMARCB1-SMARCE1-ACTB) (modification, collaborate)
  • BioCarta the information processing pathway at the ifn beta enhancer: IFN-beta nucleosome complex (RELA-ATF2-IRF5_IRF1_IRF3_IRF6_IRF7_IRF4_IRF2-JUN-HMGB1-PCAF-CREBBP-SMARCA4-SMARCD1-ARID1A-SMARCC1-SMARCC2-SMARCB1-SMARCE1-ACTB) → TAFs/TF2A/TBP/TF2F/TF2B/TF2H/TF2E/RNA POL II complex (GTF2A1-NR3C1-GTF2F1-GTF2B-GTF3A-GTF2E1-POLR2A) (modification, collaborate)
  • BioCarta the information processing pathway at the ifn beta enhancer: RELA/p50/ATF-2/IRF/c-JUN/HMG1/PCAF/CBP/hSWI/SNF complex (RELA-ATF2-IRF5_IRF1_IRF3_IRF6_IRF7_IRF4_IRF2-JUN-HMGB1-PCAF-CREBBP-SMARCA4-SMARCD1-ARID1A-SMARCC1-SMARCC2-SMARCB1-SMARCE1-ACTB) → TAFs/TF2A/TBP/TF2F/TF2B/TF2H/TF2E/RNA POL II complex (GTF2A1-NR3C1-GTF2F1-GTF2B-GTF3A-GTF2E1-POLR2A) (modification, collaborate)
  • BioCarta chromatin remodeling by hswi/snf atp-dependent complexes: NF1 → glucocorticoid/glucocorticoid receptor/glucocorticoid/glucocorticoid receptor/hSWI/SNF/NF1 complex (NR3C1-NF1-SMARCA4-SMARCD1-ARID1A-SMARCC1-SMARCC2-SMARCB1-SMARCE1-ACTB) (modification, collaborate)
  • BioCarta chromatin remodeling by hswi/snf atp-dependent complexes: glucocorticoid/glucocorticoid receptor/glucocorticoid/glucocorticoid receptor/hSWI/SNF complex (NR3C1-NF1) → glucocorticoid/glucocorticoid receptor/glucocorticoid/glucocorticoid receptor/hSWI/SNF/NF1 complex (NR3C1-NF1-SMARCA4-SMARCD1-ARID1A-SMARCC1-SMARCC2-SMARCB1-SMARCE1-ACTB) (modification, collaborate)
  • BioCarta chromatin remodeling by hswi/snf atp-dependent complexes: glucocorticoid/glucocorticoid receptor/glucocorticoid/glucocorticoid receptor/hSWI/SNF/NF1 complex (NR3C1-NF1-SMARCA4-SMARCD1-ARID1A-SMARCC1-SMARCC2-SMARCB1-SMARCE1-ACTB) → TAFs/TF2A/TBP/TF2F/TF2B/TF2H/TF2E/RNA POL II complex (GTF2A1-NR3C1-GTF2F1-GTF2B-GTF3A-GTF2E1-POLR2A) (modification, activates)
  • BioCarta control of gene expression by vitamin d receptor: NCOA62/TSC2/TRAP220 complex (SKIIP-TSC2-PPARBP) → RXR/VDR/WSTF/WINAC complex (RXRA-VDR-BAZ1B-SMARCE1-SMARCC2-SMARCC1-SMARCD1-ARID1A-SMARCA4-ACTL6A-TOP2B-CHAF1A-SUPT16H) (transcription, activates)
  • BioCarta the information processing pathway at the ifn beta enhancer: hSWI/SNF complex (SMARCA4-SMARCD1-ARID1A-SMARCC1-SMARCC2-SMARCB1-SMARCE1-ACTB) → RELA/p50/ATF-2/IRF/c-JUN/HMG1/PCAF/CBP complex (RELA-ATF2-IRF5_IRF1_IRF3_IRF6_IRF7_IRF4_IRF2-JUN-HMGB1-PCAF-CREBBP) (modification, collaborate)
  • BioCarta the information processing pathway at the ifn beta enhancer: hSWI/SNF complex (SMARCA4-SMARCD1-ARID1A-SMARCC1-SMARCC2-SMARCB1-SMARCE1-ACTB) → RELA/p50/ATF-2/IRF/c-JUN/HMG1/PCAF/CBP/hSWI/SNF complex (RELA-ATF2-IRF5_IRF1_IRF3_IRF6_IRF7_IRF4_IRF2-JUN-HMGB1-PCAF-CREBBP-SMARCA4-SMARCD1-ARID1A-SMARCC1-SMARCC2-SMARCB1-SMARCE1-ACTB) (modification, collaborate)
  • BioCarta the information processing pathway at the ifn beta enhancer: RELA/p50/ATF-2/IRF/c-JUN/HMG1/PCAF/CBP complex (RELA-ATF2-IRF5_IRF1_IRF3_IRF6_IRF7_IRF4_IRF2-JUN-HMGB1-PCAF-CREBBP) → RELA/p50/ATF-2/IRF/c-JUN/HMG1/PCAF/CBP/hSWI/SNF complex (RELA-ATF2-IRF5_IRF1_IRF3_IRF6_IRF7_IRF4_IRF2-JUN-HMGB1-PCAF-CREBBP-SMARCA4-SMARCD1-ARID1A-SMARCC1-SMARCC2-SMARCB1-SMARCE1-ACTB) (modification, collaborate)

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

Text-mined interactions from Literome

Low et al., Oncogene 1999 : Fas ligation in the presence of cycloheximide induced Jun N-terminal kinase 1 (JNK1) and JNK2 phosphorylation, caspase activation and cell death in the IL-3 dependent cell line BAF3
Lock et al., J Biol Chem 1999 : Immunoprecipitation experiments using DokR-specific antibodies revealed an interaction between endogenous DokR and a 150-kDa protein that is tyrosine phosphorylated in EGF stimulated BaF/3 cells
Delaney et al., J Neurobiol 1999 : Caspase-3 activity was rapidly activated upon serum withdrawal in SC, and the caspase inhibitor BAF blocked apoptosis
Shimamoto et al., Exp Hematol 2000 : In this study, we have constructed an expression vector encoding human DLX-7, and examined the effects of overexpression of DLX-7 in the IL-3 dependent lymphoid precursor cell line Ba/F3
Demoulin et al., FEBS Lett 2000 : We observed a PI 3-K dependent phosphorylation of protein kinase B (PKB) in TS1 cells, but not in BaF/9R , nor in other IL-9 dependent cell lines
Schutyser et al., J Immunol 2000 (Cell Transformation, Neoplastic) : Although coinduced with monocyte chemotactic protein-1 (MCP-1) and IL-8 by dsRNA, measles virus, and IL-1beta in diploid fibroblasts, leukocytes produced LARC/MIP-3alpha only in response to LPS
Sun et al., Biochem Biophys Res Commun 2001 : Treatment of the cells with mitogens [ ovine PRL, recombinant rat placental lactogen-I (PL-I) and human IL-3 ] caused a dose dependent increase in the expression of PAL31 mRNA in the PRL dependent cell line Nb2, and IL-3 dependent cell line BaF3
von Gise et al., Mol Cell Biol 2001 : Additionally, we also could extend these findings to the IL-3 dependent pro-B-cell line BaF3 , suggesting that recruitment of MEK is a common mechanism for survival signaling by activated Raf
Delaney et al., J Neuropathol Exp Neurol 2001 (Diabetic Neuropathies) : High glucose induces caspase cleavage in apoptotic SCs -- an effect that is blocked by bok-asp-fmk (BAF) , a caspase inhibitor
Zaidi et al., J Neuropathol Exp Neurol 2001 : Cell death was inhibited by 3-methyladenine, an inhibitor of autophagic vacuole formation, but not by Boc-Asp-FMK (BAF) , a broad caspase inhibitor
Goetz et al., Cancer Res 2001 (Leukemia, Myelogenous, Chronic, BCR-ABL Positive) : To determine whether Bcr-Abl and growth factors can affect the p53/Mdm2 pathway, we studied the expression of Mdm2 in the IL-3 dependent pre-B cell line BaF3 and its bcr-abl transfected derivative BaF3p185 after IL-3 deprivation or treatment with the c-Abl tyrosine kinase inhibitor STI571
Andreasson et al., Cancer Genet Cytogenet 2001 (Cell Transformation, Neoplastic...) : To investigate the influence of ETV6/CBFA2 on cellular transformation, the fusion gene was cloned into a murine ecotropic retroviral vector and transduced into IL-3 dependent Ba/F3 and 32Dcl.3 and IL-7 dependent IxN/2b murine hematopoietic cell lines
Plo et al., Oncogene 2001 : In Ba/F3-wt and in Ba/F3-Kit cells, daunorubicin stimulated within 8-15 min neutral sphingomyelinase and ceramide production but not in SCF stimulated Ba/F3-Kit or in Ba/F3-KitDelta27 whereas all Ba/F3 cells were equally sensitive to exogenous cell-permeant C6-ceramide
Xu et al., Biochem Biophys Res Commun 2001 : Using IL-2 dependent cell line BAF/BO3beta , we found that this -130EBS element can form a specific complex with nuclear protein, which contained a novel ETS transcription factor
Long et al., Apoptosis 2002 : The level of phosphorylated p53 was increased as a result of BAF or STAU-treatment
Lee et al., J Cell Sci 2001 (Muscular Dystrophy, Emery-Dreifuss) : We show that emerin binds directly to barrier-to-autointegration factor (BAF), a DNA bridging protein, and that this binding to BAF requires conserved residues in the LEM-motif of emerin
Park et al., Mol Cell Biol 2002 (Cell Transformation, Neoplastic) : Using deletion mutants of BAF53, we show that BAF53 is critical for c-Myc oncogenic activity
Dierov et al., Blood 2002 (Second Messenger Systems) : TEL/PDGF beta R transforms interleukin-3 (IL-3) dependent Ba/F3 and 32D cells to IL-3 independence and induces a murine myeloproliferative disease in a bone marrow transplantation model of leukemogenesis
Drachman et al., J Biol Chem 2002 : When expressed in the interleukin-3 dependent cell line Ba/F3 , the chimeric receptors were appropriately expressed on the cell surface and were able to initiate tyrosine kinase activity upon exposure to TPO
Mudhasani et al., Mol Cell Biol 2002 : Taken together, these data suggest that BRG-1 and, very likely, an hSWI/SNF complex are required for transcription of MHC class II genes
Habib et al., Biochemistry 2002 : Retroviral mediated transduction of wild-type gamma c into XSCID JT cells restored function to the IL-21R, as shown by IL-21 induced tyrosine phosphorylation of JAK1 and JAK3, and downstream activation of STAT5 , in JT/gamma c cells as well as BaF3/IL-21R alpha and primary splenic B cells
Chi et al., Nature 2002 : Reciprocal regulation of CD4/CD8 expression by SWI/SNF-like BAF complexes ... Reciprocal regulation of CD4/CD8 expression by SWI/SNF-like BAF complexes
Maddens et al., Blood 2002 : Results show that, in both Ba/F3 and 32D murine cell lines transfected with wild-type c-kit, stem cell factor (SCF) stimulation resulted in a significant reduction of IR-induced apoptosis and cytotoxicity, whereas DNA repair remained unaffected
Battaglioli et al., J Biol Chem 2002 : In vivo, BAF57 occupies the neuronal sodium channel gene ( Nav1.2 ) promoter, and targeting to this gene requires REST
Liu et al., Mol Cell Biol 2002 : Furthermore, we show that the ubiquitous transcription activator Sp1 interacts with the BAF complex in vivo and augments the BAF mediated activation of the IFITM3 promoter
Trowbridge et al., J Biol Chem 2002 : FGF-7 did not support cell proliferation in the absence of glycosaminoglycan or with addition of heparan sulfate or chondroitin sulfate A/C but did stimulate BaF/KGFR division in the presence of dermatan sulfate or highly sulfated low molecular weight fractions of dermatan
Paling et al., Biochem J 2002 : We have investigated in detail the role of SHP-1 in interleukin-3 (IL-3) signal transduction by inducibly expressing wild-type ( WT ), C453S ( substrate trapping ) and R459M ( catalytically inactive ) forms of SHP-1 in the IL-3 dependent cell line BaF/3
Bhat et al., J Alzheimers Dis 2002 : To determine whether these pathways interact from a signalling perspective, we compared the effects of BAF ( a general caspase inhibitor ), Li+ ( a GSK3beta inhibitor ) and insulin on NGF-W induced PC12 cell death ... To determine whether these pathways interact from a signalling perspective, we compared the effects of BAF ( a general caspase inhibitor ), Li+ ( a GSK3beta inhibitor ) and insulin on NGF-W induced PC12 cell death ... BAF inhibited caspase-3 activity and delayed cell death up to 6 h after NGF-W indicating that caspase inhibition is sufficient to prevent apoptosis ... BAF had no major effect on GSK3betaactive site phosphorylation or activity suggesting the caspase pathway does not regulate GSK3beta activity
Holaska et al., J Biol Chem 2003 : Although GCL alone can not explain the disease mechanism, our results strongly support gene expression models for Emery-Dreifuss muscular dystrophy by showing that emerin binds directly to a transcriptional repressor, GCL, and by suggesting that emerin-repressor complexes might be regulated by BAF
Bergeron et al., Clin Exp Allergy 2003 (Asthma) : In transient transfection experiments, IL-4 increased promoter activity by threefold in BAF and BNF
Gilmore et al., Virology 2003 (Cell Transformation, Neoplastic) : We also show that infection of the IL3 dependent mouse B cell line BaF3 with the MSCV-v-rel vector results in expression of v-Rel, but does not convert these cells to growth factor independence
Yamamura et al., EMBO J 1992 : We found that the expression of EPOR induced EPO dependence in IL-3 dependent BAF-B03 and IL-5 dependent Y16 cells but not in IL-2 dependent CTLL-2 cells, although the EPOR expressing CTLL-2 cell lines could bind and internalize EPO as efficiently as the BAF-B03 derived cell lines
Bayle et al., J Biol Chem 2004 : SOCS6 reduced SCF induced activation of ERK1/2 and p38 but not activation of AKT or STATs in Ba/F3 , murine embryonic fibroblast (MEF), or COS-7 cells
Kanie et al., Leukemia 2004 : TEL-Syk fusion transformed interleukin-3 (IL-3) dependent murine hematopoietic cell line BaF3 to growth factor independence
Luwor et al., Oncogene 2004 (Neoplasms) : In order to examine the signalling pathways activated by the de2-7 EGFR and its biological effects in an in vitro system, the de2-7 EGFR gene was transfected into the murine IL-3 dependent pro-B-cell line BaF/3
Dermott et al., Stem Cells 2004 : Transient expression of p205 in murine IL-3 dependent BaF3 and 32D-C123 progenitor cell lines inhibited IL-3 induced growth and proliferation
Rodriguez-Tarduchy et al., J Immunol 1992 : Calcium ionophores inhibit apoptosis in the IL-3 dependent cell line BAF3 and maintain the cells in a viable noncycling state
Suzuki et al., EMBO J 2004 : LAP2alpha stabilizes the association of BAF with the PIC to stimulate intermolecular integration and suppress autointegration
Wang et al., Genes Dev 2004 (Heart Defects, Congenital) : Importantly, BAF180 is recruited to the promoter of these target genes and BAF180 deficiency affects the RA response for CRABPII and RARbeta2
Ezoe et al., J Biol Chem 2005 : A tamoxifen-inducible form of GATA-1 ( GATA-1/ERT ) showed a minor inhibitory effect on interleukin-3 (IL-3) dependent growth of an IL-3 dependent cell line Ba/F3
Hartmann et al., Exp Hematol 2005 : We investigated the impact of imatinib on telomere length and telomerase activity of the interleukin-3 (IL-3) dependent murine pro-B cell line BaF3 and the BCR-ABL positive, IL-3 independent transfectant BaF3p185 in vitro
Lee et al., Mol Cells 2005 : The alanine replaced BAF53 mutants also stimulated p53 dependent transcription, in which the SWI/SNF and TRRAP complexes are involved
Mihara et al., Int Immunopharmacol 2005 : Tocilizumab inhibited the proliferation of BaF/IL-6R induced by IL-6 , but did not inhibit the proliferation of BaF/IL-11R, BaF/OSMR, BaF/LIFR and BaF/CNTFR cells induced by their corresponding cytokines
Nichols et al., Mol Biol Cell 2006 : Coexpression of VRK1 and GFP-BAF greatly diminishes the association of BAF with the nuclear chromatin/matrix and leads to its dispersal throughout the cell
Foster et al., Oncogene 2006 : Activation of Akt in HeLa cells resulted in its association with hSWI/SNF subunits : INI1, BAF155 and BAF170, as well as actin
Jacque et al., Nature 2006 : Barrier-to-autointegration factor (BAF) , the LEM ( LAP, emerin, MAN ) binding partner of emerin, was required for the association of viral cDNA with emerin and for the ability of emerin to support virus infection
Chang et al., Oncogene 1991 : In this study, we have measured the effects of interleukin 3 (IL-3) deprivation and restimulation on c-myc promoter usage in the IL-3 dependent pre-B cell line Ba/F3
Yoshikawa et al., Arch Otolaryngol Head Neck Surg 2006 (Cholesteatoma, Middle Ear) : The messenger RNA expressions of LARC ( liver and activation regulated chemokine ), GMCSF ( granulocyte-macrophage colony stimulating factor ), epiregulin, ICAM1 ( intercellular adhesion molecule 1 ), and TGFA ( transforming growth factor alpha ) were more strongly up-regulated by IL-1alpha and/or IL-1beta in MECF than in SF, suggesting that these fibroblasts derived from different tissues retained their typical gene expression profiles ... The messenger RNA expressions of LARC ( liver and activation regulated chemokine ), GMCSF ( granulocyte-macrophage colony stimulating factor ), epiregulin, ICAM1 ( intercellular adhesion molecule 1 ), and TGFA ( transforming growth factor alpha ) were more strongly up-regulated by IL-1alpha and/or IL-1beta in MECF than in SF, suggesting that these fibroblasts derived from different tissues retained their typical gene expression profiles
Fukunaga et al., EMBO J 1991 : Introduction of G-CSF receptor cDNA into IL-3 dependent murine myeloid cell line FDC-P1 and pro-B cell line BAF-B03 , which normally do not respond to G-CSF, enabled them to proliferate in response to G-CSF
Wang et al., J Biochem 2007 : In this study, we show that BAF53 is involved in the repression of p53 dependent p21-gene transcription by interacting with p53 both in vivo and in vitro ... In this study, we show that BAF53 is involved in the repression of p53 dependent p21-gene transcription by interacting with p53 both in vivo and in vitro
Furukawa et al., J Struct Biol 2007 : This BAF loss was not detected before drICE activation and was inhibited by Ac-DEVD-CHO caspase inhibitors
Cuddapah et al., FEBS Lett 2008 : We show that the BAF complex mediated induction of IFITM3 is dependent on binding of the transcriptional enhancer factor 1 ( TEF-1/TEAD1 ) to the M-CAT like elements of its promoter ... TEF-1 knock-down reduced the BAF complex mediated activation of IFITM3 promoter
Basham et al., Nucleic Acids Res 2008 (Neoplasms) : Subsequent gene expression profiling and RT-qPCR analyses of IL-3 stimulated Ba/F3-beta cells led to the identification of putative novel STAT5 target genes
Sogo et al., J Immunol Methods 2008 : When the pairs of chimeric receptors ( V ( H ) -IL-2Rbeta and V ( L ) -IL-2Rgamma, or V ( H ) -IL-2Rgamma and V ( L ) -IL-2Rbeta ) were expressed in IL-3 dependent pro-B cell line Ba/F3 and IL-2 dependent T cell line CTLL-2, the cognate antigen HEL induced selective expansion of gene modified cells in the absence of IL-3 and IL-2, respectively
Yamane et al., Biosci Rep 2008 : We have identified a series of novel non-peptide compounds that activate the thrombopoietin dependent cell line Ba/F3-huMPL
Shinjyo et al., Tohoku J Exp Med 2008 (MAP Kinase Signaling System) : Here we analyzed downstream pathways of Ras in interleukin-3 (IL-3) dependent Baf-3 murine derived pro-B lymphocytic cells that express constitutively active Ras mutants, using signaling pathway-specific inhibitors
Lai et al., Proc Natl Acad Sci U S A 2009 : BAF57 RNAi and BAF57 dominant negative mutants defective in CaM binding similarly impair the induction of BAF target genes
Wan et al., Eur J Immunol 2009 : The Brg1/Brm associated factor (BAF) chromatin remodeling complex directly binds the CD4 silencer and is essential for CD4 repression during T-cell development, because deletion of the ATPase subunit Brg1 or a dominant negative mutant of BAF57 each impairs CD4 repression in early thymocytes
Sogo et al., Cytokine 2009 : When the chimeras were co-expressed in IL-3 dependent pro-B cell line Ba/F3 and IL-2 dependent T cell line CTLL-2, gene modified cells were selectively expanded in the absence of IL-3 and IL-2, respectively, by adding fluorescein conjugated BSA ( BSA-FL ) as a cognate antigen
Furuhata et al., Biochem Biophys Res Commun 2009 : Like JAK2V617F overexpression, constitutively active STAT5 or STAT3 induced aberrant p27 ( Kip1 ) expression of Ba/F3 cells ... Like JAK2V617F overexpression, constitutively active STAT5 or STAT3 induced aberrant p27 ( Kip1 ) expression of Ba/F3 cells
Oya et al., J Biol Chem 2009 (MAP Kinase Signaling System) : WINAC dependent transcriptional regulation of vitamin D receptor was consequently impaired by this WSTF mutation, but the recovery from DNA damage mediated by WICH was not impaired
Chintagari et al., PloS one 2010 : The dissipation of lamellar body pH gradient by Bafilomycin A1 (Baf A1) , an inhibitor of V-ATPase , increased surfactant secretion
Choi et al., Mol Pharmacol 2010 (Breast Neoplasms) : Furthermore, treatment with 3MA markedly down-regulated capsaicin induced p38 activation and LC3 conversion, and BaF1 completely down-regulated ERK activation and led to LC3II accumulation ... Furthermore, treatment with 3MA markedly down-regulated capsaicin induced p38 activation and LC3 conversion, and BaF1 completely down-regulated ERK activation and led to LC3II accumulation
Gündogdu et al., Molecular cancer 2010 : Using the murine IL3 dependent cell line BaF3 we investigated the influence of RhoH protein expression levels on IL3 mediated cellular responses
Keppler et al., J Biol Chem 2010 : We show that the mechanism of BAF155 mediated stabilization of BAF57 involves blocking its ubiquitination by preventing interaction with TRIP12, an E3 ubiquitin ligase
Tao et al., Hepatology 2011 : At the molecular level, BAF60a activates Bmal1 and G6Pase transcription by way of the coactivation of retinoid related orphan receptor alpha ( RORa )
Wurster et al., BMC immunology 2012 : BAF180 binds directly to regulatory elements in the Il-10 locus but is replaced by BAF250 BAF complexes in the absence of BAF180, resulting in increased histone acetylation and CBP recruitment to the IL-10 locus
Maiwald et al., BMC systems biology 2012 : Application to the JAK-STAT signaling pathway in Epo stimulated BaF3-EpoR cells enabled the calculation of the time dependent label half-life and transit-time of STAT species
Chandler et al., Mol Cell Biol 2013 : Using a THBS1 promoter-reporter gene, we further show that BAF-A directly regulates THBS1 promoter activity in an ARID domain dependent manner
Dykhuizen et al., Nature 2013 (Medulloblastoma) : Endogenous BAF complexes interact directly with endogenous topoisomerase IIa ( TOP2A ) through BAF250a and are required for the binding of TOP2A to approximately 12,000 sites across the genome
Ascaso et al., Eur J Immunol 1994 : The topoisomerase II inhibitor etoposide causes a more rapid onset of apoptosis in the IL-3 dependent cell line BAF3 , deprived of IL-3
Avalos et al., Blood 1995 : To identify critical regions mediating growth signal transduction by hG-CSFR, deletions or site directed amino acid substitutions were introduced into the cytoplasmic domain of hG-CSFR, and the mutant cDNAs were transfected into the murine interleukin-3 (IL-3) dependent Ba/F3 and FDCP cell lines
Caldenhoven et al., J Biol Chem 1995 (Acute-Phase Reaction) : Moreover, endogenous STAT3 was tyrosine phosphorylated and activated in human IL-5 stimulated BaF3 cells ectopically expressing the human IL-5R ( BaF3/IL5R )
van Weert et al., J Cell Biol 1995 : Toward this purpose, bafilomycin A1 (Baf) , a specific inhibitor of the vacuolar proton pump , was used to inhibit acidification of the vacuolar system
Calvo et al., Eur J Immunol 1994 : Proliferation of the IL-3 dependent pro-B cell line Ba/F3 transfected with the EPOR ( Ba/F3-EPOR ) can be supported by either IL-3 or EPO
Howard et al., J Rheumatol 1993 : To determine if bone associated peptide factors (BAF) differentially affect proteoglycan and hyaluronic acid ( HA ) synthesis as a result of the maturity of the animal and of the location of chondrocytes within cartilage zones
Palokangas et al., J Biol Chem 1994 : Bafilomycin A1 ( Baf ) , a specific inhibitor of the vacuolar-type proton pump , inhibited the entry of Semliki Forest virus and vesicular stomatitis virus into BHK-21 cells
Kawahara et al., Mol Cell Biol 1994 : In the present study, we examined the functional role of the IL-2R gamma cytoplasmic region in the IL-3 dependent mouse hematopoietic cell line BAF-B03 , which expresses the endogenous IL-2R alpha and IL-2R gamma, or its subline F7, which additionally expresses human IL-2R beta cDNA
Weiss et al., Blood 1993 : To study these truncations, we stably transfected the IL-3 dependent murine cell line Ba/F3 with wild-type or mutant cDNAs
Sakamaki et al., J Biol Chem 1993 : These chimeric receptors and normal cytokine receptors were expressed in an IL-3 dependent murine pro-B cell line, Ba/F3 , and an IL-2 dependent murine T cell line, CTLL2
Vigon et al., Oncogene 1993 : A chimeric receptor containing the extracellular domain of the granulocyte colony stimulating factor ( G-CSF) receptor fused to the transmembrane and cytoplasmic domains of Mpl was able to induce G-CSF responsiveness when transfected into the interleukin 3 (IL-3) dependent cell line BAF/BO3
Athanasiou et al., Oncogene 1996 : A drug-selectable retrovirus expressing p135Gag-Myb-Ets induced an erythropoietin(Epo)-responsive phenotype in the cell lines FDC-P2, BaF3 and 32Dc123. Gag-Myb-Ets expression alone did not increase expression of GATA-1 or the Epo receptor(EpoR) in the presence of IL3 , and infected cell lines express increased GATA-1 and EpoR only when IL3 was replaced by Epo in the culture media ... A drug-selectable retrovirus expressing p135Gag-Myb-Ets induced an erythropoietin(Epo)-responsive phenotype in the cell lines FDC-P2, BaF3 and 32Dc123. Gag-Myb-Ets expression alone did not increase expression of GATA-1 or the Epo receptor(EpoR) in the presence of IL3, and infected cell lines express increased GATA-1 and EpoR only when IL3 was replaced by Epo in the culture media ... A drug-selectable retrovirus expressing p135Gag-Myb-Ets induced an erythropoietin(Epo)-responsive phenotype in the cell lines FDC-P2, BaF3 and 32Dc123. Gag-Myb-Ets expression alone did not increase expression of GATA-1 or the Epo receptor(EpoR) in the presence of IL3, and infected cell lines express increased GATA-1 and EpoR only when IL3 was replaced by Epo in the culture media
Heinzen et al., Infect Immun 1996 : The presence of the vacuolar-type ( H+ ) ATPase ( V-ATPase ) within the Coxiella vacuolar membrane was demonstrated by indirect immunofluorescence, and growth of C. burnetii was inhibited by bafilomycin A1 (Baf A) , a specific inhibitor of the V-ATPase
Collins et al., J Cell Sci 1996 : DNA fragmentation in isolated nuclei from the murine IL3 dependent bone marrow cell line BAF3 could be stimulated either by decreasing pH below 6.5 or by adding microM calcium at neutral pH
Deshmukh et al., J Cell Biol 1996 : At similar concentrations, BAF also blocked the NGF deprivation induced death of rat sympathetic neurons in culture
Ikushima et al., Proc Natl Acad Sci U S A 1997 : The expression and binding activity of the Nfil3 protein ( also called E4bp4 ), but not of Hlf, Dbp, or Tef, was found to be regulated by IL-3 in mouse pro-B cell lines ( Baf-3 and FL5.12 )
Barber et al., Blood 1997 : Erythropoietin (EPO) and interleukin-3 induced a dose and time dependent tyrosine phosphorylation of Cbl in both EPO dependent Ba/F3 and DA-3 transfectants, and the erythroid cell line HCD-57
Zhao et al., Cell 1998 : PIP2 , which is regulated by activation stimuli, is sufficient in vitro to target the BAF complex to chromatin, but it has no effect on related chromatin remodeling complexes containing SNF2L or hISWI ... beta-actin and BAF53 are required for maximal ATPase activity of BRG1 and are also required with BRG1 for association of the complex with chromatin/matrix
Tsujimura et al., Blood 1999 (Cell Transformation, Neoplastic...) : When c-kitDel-Wild and c-kitDel-Tyr814 genes were introduced into a murine interleukin-3 (IL-3) dependent cell line Ba/F3 , KITDel-Tyr814 was constitutively phosphorylated on tyrosine and activated, whereas KITDel-Wild was not