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IRF6 — IRG1
Text-mined interactions from Literome
Sugiyama et al., Microbiol Immunol 2004
:
2-AP also reduced the expression of IFN-beta and IFN-inducible genes, such as IFN-gamma-inducible protein ( IP ) -10 and
immune-responsive gene (IRG)-1 , and the inducible type of NO synthase (iNOS) mRNA in
response to
LPS
Lee et al., Immunogenetics 1995
:
The role of the protein kinase A pathway in regulating the
induction of
IRG1 by
LPS is questionable, because although forskolin inhibited its induction, neither dibutyrl-cAMP nor 8- ( 4-chlorophenylthio ) -cAMP had much effect on its expression ... Inhibiting tyrosine phosphorylation abrogated the
induction of
IRG1 by
LPS ... Hence, the
induction of
IRG1 by
LPS is mediated by tyrosine kinase and protein kinase C pathway