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AHSA1 — SYK

Text-mined interactions from Literome

He et al., Antioxid Redox Signal 2002 : Syk is required for p38 activation and G2/M arrest in B cells exposed to oxidative stress ... In this study, we have investigated the role of Syk in p38 activation and the regulation of cell-cycle progression upon oxidative stress ... Syk is required for p38 activation following stimulation with 10-100 microM H ( 2 ) O ( 2 ), but not with 1 mM H ( 2 ) O ( 2 )
Ulanova et al., Biochem Biophys Res Commun 2006 : Inhibition of Syk down-regulated TNF induced p38 and p44/42 MAPK phosphorylation and nuclear translocation of p65 NF-kappaB
Wang et al., J Immunol 2006 : ICAM-1 engagement by HRV and cross linking Abs also induced phosphorylation of p38 in a Syk dependent manner, and conversely, knockdown of Syk by short interfering ( si ) RNA substantially diminished p38 activation and IL-8 gene expression
Lau et al., J Immunol 2008 : We recently demonstrated the Syk tyrosine kinase to be an important mediator of HRV-ICAM-1 signaling : Syk regulates replication independent p38 MAPK activation and IL-8 expression